Long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological study

Many motor skills, once acquired, are stored over a long time period, probably sustained by permanent neuronal changes. Thus, in this paper we have investigated with quantitative stereology the generation and persistence of neuronal density changes in primary motor cortex (MI) following motor skill...

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Autor principal:	MORALES,PAOLA
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2008
Materias:	Motor cortex plasticity persistence of structural changes aging motor skill learning (skilled reaching task) stereology rat
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000400005
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spelling	oai:scielo:S0716-976020080004000052009-06-16Long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological studyMORALES,PAOLA Motor cortex plasticity persistence of structural changes aging motor skill learning (skilled reaching task) stereology rat Many motor skills, once acquired, are stored over a long time period, probably sustained by permanent neuronal changes. Thus, in this paper we have investigated with quantitative stereology the generation and persistence of neuronal density changes in primary motor cortex (MI) following motor skill learning (skilled reaching task). Rats were trained a lateralised reaching task during an "early" (22-31 days oíd) or "late" (362-371 days oíd) postnatal period. The trained and corresponding control rats were sacrificed at day 372, immediately after the behavioural testing. The "early" trained group preserved the learned skilled reaching task when tested at day 372, without requiring any additional training. The "late" trained group showed a similar capacity to that of the "early" trained group for learning the skilled reaching task. All trained animáis ("early" and "late" trained groups) showed a significant Ínter hemispheric decrease of neuronal density in the corresponding motor forelimb representation área of MI (cortical layers II-III)info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.41 n.4 20082008-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000400005en10.4067/S0716-97602008000400005
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Motor cortex plasticity persistence of structural changes aging motor skill learning (skilled reaching task) stereology rat
spellingShingle	Motor cortex plasticity persistence of structural changes aging motor skill learning (skilled reaching task) stereology rat MORALES,PAOLA Long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological study
description	Many motor skills, once acquired, are stored over a long time period, probably sustained by permanent neuronal changes. Thus, in this paper we have investigated with quantitative stereology the generation and persistence of neuronal density changes in primary motor cortex (MI) following motor skill learning (skilled reaching task). Rats were trained a lateralised reaching task during an "early" (22-31 days oíd) or "late" (362-371 days oíd) postnatal period. The trained and corresponding control rats were sacrificed at day 372, immediately after the behavioural testing. The "early" trained group preserved the learned skilled reaching task when tested at day 372, without requiring any additional training. The "late" trained group showed a similar capacity to that of the "early" trained group for learning the skilled reaching task. All trained animáis ("early" and "late" trained groups) showed a significant Ínter hemispheric decrease of neuronal density in the corresponding motor forelimb representation área of MI (cortical layers II-III)
author	MORALES,PAOLA
author_facet	MORALES,PAOLA
author_sort	MORALES,PAOLA
title	Long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological study
title_short	Long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological study
title_full	Long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological study
title_fullStr	Long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological study
title_full_unstemmed	Long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological study
title_sort	long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological study
publisher	Sociedad de Biología de Chile
publishDate	2008
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000400005
work_keys_str_mv	AT moralespaola longlastingstructuralchangesinprimarymotorcortexaftermotorskilllearningabehaviouralandstereologicalstudy
_version_	1718441438733139968

Long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological study

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