Superoxide dismutase and catalase: tissue activities and relation with age in the long-lived species Margaritifera margaritifera

Free radicals are extremely reactive and produce damage and modify cell functions. Furthermore, superoxide dismutase and catalase are believed to play a key role in the enzymatic defence of the cells. Indeed, some authors have argued that reduced free-radical damage could explain increased longevity...

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Autores principales:	FERNÁNDEZ,CARLOS, SAN MIGUEL,EDUARDO, FERNÁNDEZ-BRIERA,ALMUDENA
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2009
Materias:	Margaritifera margaritifera free radicals aging superoxide dismutase catalase
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000100006
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spelling	oai:scielo:S0716-976020090001000062009-06-11Superoxide dismutase and catalase: tissue activities and relation with age in the long-lived species Margaritifera margaritiferaFERNÁNDEZ,CARLOSSAN MIGUEL,EDUARDOFERNÁNDEZ-BRIERA,ALMUDENA Margaritifera margaritifera free radicals aging superoxide dismutase catalase Free radicals are extremely reactive and produce damage and modify cell functions. Furthermore, superoxide dismutase and catalase are believed to play a key role in the enzymatic defence of the cells. Indeed, some authors have argued that reduced free-radical damage could explain increased longevity. Margaritifera margaritifera is one of the longest-lived animals in the world (up to 100-200 years). Furthermore, this organism may serve as a useful model for gerontologists interested in exploring the mechanisms that promote long life and the slowing of senescence. The present study estimated for the first time individual enzymatic activity for superoxide dismutase isozymes (Cu,Zn-SOD and Mn-SOD) and catalase in tissue preparations of gills, digestive glands and mantles of two natural populations of M. margaritifera. Superoxide dismutase activities showed significant differences in the tissues analysed of specimens from the same river and in specimens from different rivers for the same tissue. Catalase activity levels also showed significant variation, but differences among tissues, within tissues or between rivers were of relatively little interest. We failed to find any relationship between individual enzymatic activities and the age estimated for each mussel. Indeed, the wide variation found in activity levels can be principally interpreted as an adaptation to the unpredictable and changing nature of freshwater natural habitats.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.42 n.1 20092009-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000100006en10.4067/S0716-97602009000100006
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Margaritifera margaritifera free radicals aging superoxide dismutase catalase
spellingShingle	Margaritifera margaritifera free radicals aging superoxide dismutase catalase FERNÁNDEZ,CARLOS SAN MIGUEL,EDUARDO FERNÁNDEZ-BRIERA,ALMUDENA Superoxide dismutase and catalase: tissue activities and relation with age in the long-lived species Margaritifera margaritifera
description	Free radicals are extremely reactive and produce damage and modify cell functions. Furthermore, superoxide dismutase and catalase are believed to play a key role in the enzymatic defence of the cells. Indeed, some authors have argued that reduced free-radical damage could explain increased longevity. Margaritifera margaritifera is one of the longest-lived animals in the world (up to 100-200 years). Furthermore, this organism may serve as a useful model for gerontologists interested in exploring the mechanisms that promote long life and the slowing of senescence. The present study estimated for the first time individual enzymatic activity for superoxide dismutase isozymes (Cu,Zn-SOD and Mn-SOD) and catalase in tissue preparations of gills, digestive glands and mantles of two natural populations of M. margaritifera. Superoxide dismutase activities showed significant differences in the tissues analysed of specimens from the same river and in specimens from different rivers for the same tissue. Catalase activity levels also showed significant variation, but differences among tissues, within tissues or between rivers were of relatively little interest. We failed to find any relationship between individual enzymatic activities and the age estimated for each mussel. Indeed, the wide variation found in activity levels can be principally interpreted as an adaptation to the unpredictable and changing nature of freshwater natural habitats.
author	FERNÁNDEZ,CARLOS SAN MIGUEL,EDUARDO FERNÁNDEZ-BRIERA,ALMUDENA
author_facet	FERNÁNDEZ,CARLOS SAN MIGUEL,EDUARDO FERNÁNDEZ-BRIERA,ALMUDENA
author_sort	FERNÁNDEZ,CARLOS
title	Superoxide dismutase and catalase: tissue activities and relation with age in the long-lived species Margaritifera margaritifera
title_short	Superoxide dismutase and catalase: tissue activities and relation with age in the long-lived species Margaritifera margaritifera
title_full	Superoxide dismutase and catalase: tissue activities and relation with age in the long-lived species Margaritifera margaritifera
title_fullStr	Superoxide dismutase and catalase: tissue activities and relation with age in the long-lived species Margaritifera margaritifera
title_full_unstemmed	Superoxide dismutase and catalase: tissue activities and relation with age in the long-lived species Margaritifera margaritifera
title_sort	superoxide dismutase and catalase: tissue activities and relation with age in the long-lived species margaritifera margaritifera
publisher	Sociedad de Biología de Chile
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000100006
work_keys_str_mv	AT fernandezcarlos superoxidedismutaseandcatalasetissueactivitiesandrelationwithageinthelonglivedspeciesmargaritiferamargaritifera AT sanmigueleduardo superoxidedismutaseandcatalasetissueactivitiesandrelationwithageinthelonglivedspeciesmargaritiferamargaritifera AT fernandezbrieraalmudena superoxidedismutaseandcatalasetissueactivitiesandrelationwithageinthelonglivedspeciesmargaritiferamargaritifera
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Superoxide dismutase and catalase: tissue activities and relation with age in the long-lived species Margaritifera margaritifera

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