The proapoptotic activity of C-terminal domain of apoptosis-inducing factor (AIF) is separated from its N-terminal

The proapoptotic activity of C-terminal domain of apoptosis-inducing factor (AIF) is separated from its N-terminal

Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein that mediates both NADH-oxidizing and caspase-independent apoptosis. Further, the proapoptotic activity of AIF is located in the C-terminus of AIF, although the precise minimum sequence responsible for apoptosis induction remains to be...

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Main Authors: ZHANG,YONG, HAN,TAO, ZHU,QING, ZHANG,WEI, BAO,WEI, FU,HAI-JING, YANG,JIE, HUANG,XIAO-JUN, WEI,JUN-XIA, MENG,YAN-LING, ZHAO,JING, CAO,YUN-XIN, JIA,LIN-TAO, YANG,AN-GANG
Language:English
Published: Sociedad de Biología de Chile 2009
Subjects:
apoptosis inducing factor (AIF)
apoptosis
cytochrome c
mitochondria
HER2
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000200014
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