Cyclosporin A-treated Dendritic Cells may affect the outcome of organ transplantation by decreasing CD4+CD25+ regulatory T cell proliferation

Cyclosporin A-treated Dendritic Cells may affect the outcome of organ transplantation by decreasing CD4+CD25+ regulatory T cell proliferation

One of the mechanisms for generation of tolerance involves immature dendritic cells (DCs) and a subpopulation of regulatory CD4+ CD25+ T lymphocytes (T REG). The purpose of this work was to analyze how Cyclosporine A (CsA), a widely used immunosuppressive drug, may affect T REG proliferation. Purifi...

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Autores principales: Pino-Lagos,Karina, Michea,Paula, Sauma,Daniela, Alba,Andrea, Morales,Jorge, Bono,María Rosa, Fierro,Alberto, Rosemblatt,Mario
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2010
Materias:
CD4+CD25+ regulatory T cell
Cyclosporine A
dendritic cells
transplant tolerance
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000300010
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