Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents
This study evaluated the antiulcer activity of an ethanolic extract of Encholirium spectabile (ES-EtOH) by using different standard experimental models of induced acute gastric ulceration. ES-EtOH (100 mg/kg p.o) protected the gastric mucosa against ulceration that was induced by absolute ethanol (5...
Guardado en:
| Autores principales: | , , , , , , , , |
|---|---|
| Lenguaje: | English |
| Publicado: |
Sociedad de Biología de Chile
2010
|
| Materias: | |
| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000400011 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:scielo:S0716-97602010000400011 |
|---|---|
| record_format |
dspace |
| spelling |
oai:scielo:S0716-976020100004000112011-02-01Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodentsMoraes de Carvalho,Katharinne IFernandes,Hélio BFrota Machado,Flávia DOliveira,Irisdalva SOliveira,Francisco ANunes,Paulo Humberto MLima,Julianeli TSilva Almeida,Jackson R GMeneses Oliveira,Rita C antioxidant antiulcer activity Encholirium spectabile Bromeliaceae This study evaluated the antiulcer activity of an ethanolic extract of Encholirium spectabile (ES-EtOH) by using different standard experimental models of induced acute gastric ulceration. ES-EtOH (100 mg/kg p.o) protected the gastric mucosa against ulceration that was induced by absolute ethanol (53%), ethanol/HCl (75 %), ibuprofen (52 %) and ischemia/reperfusion (43 %). It also restored catalase activity and non-protein sulfhydryl group concentration in the gastric wall of mice that had been treated with ethanol. The pre-treatment of mice with N-nitro-L-arginine (70 mg/kg i.p.) abolished the protective activity of ES-EtOH, which indicates that prostaglandins, antioxidant compounds and nitric oxide synthase activity are involved in the gastroprotective activity of the extract.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.43 n.4 20102010-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000400011en10.4067/S0716-97602010000400011 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
antioxidant antiulcer activity Encholirium spectabile Bromeliaceae |
| spellingShingle |
antioxidant antiulcer activity Encholirium spectabile Bromeliaceae Moraes de Carvalho,Katharinne I Fernandes,Hélio B Frota Machado,Flávia D Oliveira,Irisdalva S Oliveira,Francisco A Nunes,Paulo Humberto M Lima,Julianeli T Silva Almeida,Jackson R G Meneses Oliveira,Rita C Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents |
| description |
This study evaluated the antiulcer activity of an ethanolic extract of Encholirium spectabile (ES-EtOH) by using different standard experimental models of induced acute gastric ulceration. ES-EtOH (100 mg/kg p.o) protected the gastric mucosa against ulceration that was induced by absolute ethanol (53%), ethanol/HCl (75 %), ibuprofen (52 %) and ischemia/reperfusion (43 %). It also restored catalase activity and non-protein sulfhydryl group concentration in the gastric wall of mice that had been treated with ethanol. The pre-treatment of mice with N-nitro-L-arginine (70 mg/kg i.p.) abolished the protective activity of ES-EtOH, which indicates that prostaglandins, antioxidant compounds and nitric oxide synthase activity are involved in the gastroprotective activity of the extract. |
| author |
Moraes de Carvalho,Katharinne I Fernandes,Hélio B Frota Machado,Flávia D Oliveira,Irisdalva S Oliveira,Francisco A Nunes,Paulo Humberto M Lima,Julianeli T Silva Almeida,Jackson R G Meneses Oliveira,Rita C |
| author_facet |
Moraes de Carvalho,Katharinne I Fernandes,Hélio B Frota Machado,Flávia D Oliveira,Irisdalva S Oliveira,Francisco A Nunes,Paulo Humberto M Lima,Julianeli T Silva Almeida,Jackson R G Meneses Oliveira,Rita C |
| author_sort |
Moraes de Carvalho,Katharinne I |
| title |
Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents |
| title_short |
Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents |
| title_full |
Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents |
| title_fullStr |
Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents |
| title_full_unstemmed |
Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents |
| title_sort |
antiulcer activity of ethanolic extract of encholirium spectabile mart. ex schult & schult f. (bromeliaceae) in rodents |
| publisher |
Sociedad de Biología de Chile |
| publishDate |
2010 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000400011 |
| work_keys_str_mv |
AT moraesdecarvalhokatharinnei antiulceractivityofethanolicextractofencholiriumspectabilemartexschultampschultfbromeliaceaeinrodents AT fernandesheliob antiulceractivityofethanolicextractofencholiriumspectabilemartexschultampschultfbromeliaceaeinrodents AT frotamachadoflaviad antiulceractivityofethanolicextractofencholiriumspectabilemartexschultampschultfbromeliaceaeinrodents AT oliveirairisdalvas antiulceractivityofethanolicextractofencholiriumspectabilemartexschultampschultfbromeliaceaeinrodents AT oliveirafranciscoa antiulceractivityofethanolicextractofencholiriumspectabilemartexschultampschultfbromeliaceaeinrodents AT nunespaulohumbertom antiulceractivityofethanolicextractofencholiriumspectabilemartexschultampschultfbromeliaceaeinrodents AT limajulianelit antiulceractivityofethanolicextractofencholiriumspectabilemartexschultampschultfbromeliaceaeinrodents AT silvaalmeidajacksonrg antiulceractivityofethanolicextractofencholiriumspectabilemartexschultampschultfbromeliaceaeinrodents AT menesesoliveiraritac antiulceractivityofethanolicextractofencholiriumspectabilemartexschultampschultfbromeliaceaeinrodents |
| _version_ |
1718441468363800576 |