Internucleotide correlations and nucleotide periodicity in Drosophila mtDNA: New evidence for panselective evolution

Analysis for the homogeneity of the distribution of the second base of dinucleotides in relation to the first, whose bases are separated by 0, 1, 2,... 21 nucleotide sites, was performed with the VIH-1 genome (cDNA), the Drosophila mtDNA, the Drosophila Torso gene and the human p-globin gene. These...

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Autor principal:	Valenzuela,Carlos Y
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2010
Materias:	nucleotide heterogeneity DNA periodicity dinucleotide analysis neutral evolution panselective evolution
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000400014
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spelling	oai:scielo:S0716-976020100004000142011-02-01Internucleotide correlations and nucleotide periodicity in Drosophila mtDNA: New evidence for panselective evolutionValenzuela,Carlos Y nucleotide heterogeneity DNA periodicity dinucleotide analysis neutral evolution panselective evolution Analysis for the homogeneity of the distribution of the second base of dinucleotides in relation to the first, whose bases are separated by 0, 1, 2,... 21 nucleotide sites, was performed with the VIH-1 genome (cDNA), the Drosophila mtDNA, the Drosophila Torso gene and the human p-globin gene. These four DNA segments showed highly significant heterogeneities of base distributions that cannot be accounted for by neutral or nearly neutral evolution or by the "neighbor influence" of nucleotides on mutation rates. High correlations are found in the bases of dinucleotides separated by 0, 1 and more number of sites. A periodicity of three consecutive significance values (measured by the x²9) was found only in Drosophila mtDNA. This periodicity may be due to an unknown structure or organization of mtDNA. This non-random distribution of the two bases of dinucleotides widespread throughout these DNA segments is rather compatible with panselective evolution and generalized internucleotide co-adaptation.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.43 n.4 20102010-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000400014en10.4067/S0716-97602010000400014
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	nucleotide heterogeneity DNA periodicity dinucleotide analysis neutral evolution panselective evolution
spellingShingle	nucleotide heterogeneity DNA periodicity dinucleotide analysis neutral evolution panselective evolution Valenzuela,Carlos Y Internucleotide correlations and nucleotide periodicity in Drosophila mtDNA: New evidence for panselective evolution
description	Analysis for the homogeneity of the distribution of the second base of dinucleotides in relation to the first, whose bases are separated by 0, 1, 2,... 21 nucleotide sites, was performed with the VIH-1 genome (cDNA), the Drosophila mtDNA, the Drosophila Torso gene and the human p-globin gene. These four DNA segments showed highly significant heterogeneities of base distributions that cannot be accounted for by neutral or nearly neutral evolution or by the "neighbor influence" of nucleotides on mutation rates. High correlations are found in the bases of dinucleotides separated by 0, 1 and more number of sites. A periodicity of three consecutive significance values (measured by the x²9) was found only in Drosophila mtDNA. This periodicity may be due to an unknown structure or organization of mtDNA. This non-random distribution of the two bases of dinucleotides widespread throughout these DNA segments is rather compatible with panselective evolution and generalized internucleotide co-adaptation.
author	Valenzuela,Carlos Y
author_facet	Valenzuela,Carlos Y
author_sort	Valenzuela,Carlos Y
title	Internucleotide correlations and nucleotide periodicity in Drosophila mtDNA: New evidence for panselective evolution
title_short	Internucleotide correlations and nucleotide periodicity in Drosophila mtDNA: New evidence for panselective evolution
title_full	Internucleotide correlations and nucleotide periodicity in Drosophila mtDNA: New evidence for panselective evolution
title_fullStr	Internucleotide correlations and nucleotide periodicity in Drosophila mtDNA: New evidence for panselective evolution
title_full_unstemmed	Internucleotide correlations and nucleotide periodicity in Drosophila mtDNA: New evidence for panselective evolution
title_sort	internucleotide correlations and nucleotide periodicity in drosophila mtdna: new evidence for panselective evolution
publisher	Sociedad de Biología de Chile
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000400014
work_keys_str_mv	AT valenzuelacarlosy internucleotidecorrelationsandnucleotideperiodicityindrosophilamtdnanewevidenceforpanselectiveevolution
_version_	1718441469220487168

Internucleotide correlations and nucleotide periodicity in Drosophila mtDNA: New evidence for panselective evolution

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