Insulin is secreted upon glucose stimulation by both gastrointestinal enteroendocrine K-cells and L-cells engineered with the preproinsulin gene

Transgenic mice carrying the human insulin gene driven by the K-cell glucose-dependent insulinotropic peptide (GIP) promoter secrete insulin and display normal glucose tolerance tests after their pancreatic p-cells have been destroyed. Establishing the existence of other types of cells that can proc...

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Autores principales: Encina,Gonzalo, Ezquer,Fernando, Conget,Paulette, Israel,Yedy
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2011
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000300012
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