Stem cells: sources and therapies

The historical, lexical and conceptual issues embedded in stem cell biology are reviewed from technical, ethical, philosophical, judicial, clinical, economic and biopolitical perspectives. The mechanisms assigning the simultaneous capacity to self-renew and to differentiate to stem cells (immortal t...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Monti,Manuela, Perotti,Cesare, Del Fante,Claudia, Cervio,Marila, Redi,Carlo Alberto
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2012
Materias:	embryonic stem cell adult stem cell pluripotency induced pluripotent stem cells umbilical cord blood spinal cord stroke Parkinson' disease
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300002
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0716-97602012000300002
record_format	dspace
spelling	oai:scielo:S0716-976020120003000022012-12-14Stem cells: sources and therapiesMonti,ManuelaPerotti,CesareDel Fante,ClaudiaCervio,MarilaRedi,Carlo Alberto embryonic stem cell adult stem cell pluripotency induced pluripotent stem cells umbilical cord blood spinal cord stroke Parkinson' disease The historical, lexical and conceptual issues embedded in stem cell biology are reviewed from technical, ethical, philosophical, judicial, clinical, economic and biopolitical perspectives. The mechanisms assigning the simultaneous capacity to self-renew and to differentiate to stem cells (immortal template DNA and asymmetric division) are evaluated in the light of the niche hypothesis for the stemness state. The induction of cell pluripotency and the different stem cells sources are presented (embryonic, adult and cord blood). We highlight the embryonic and adult stem cell properties and possible therapies while we emphasize the particular scientific and social values of cord blood donation to set up cord blood banks. The current scientific and legal frameworks of cord blood banks are reviewed at an international level as well as allogenic, dedicated and autologous donations. The expectations and the challenges in relation to present-day targeted diseases like diabetes mellitus type I, Parkinson's disease and myocardial infarction are evaluated in the light of the cellular therapies for regenerative medicine.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.45 n.3 20122012-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300002en10.4067/S0716-97602012000300002
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	embryonic stem cell adult stem cell pluripotency induced pluripotent stem cells umbilical cord blood spinal cord stroke Parkinson' disease
spellingShingle	embryonic stem cell adult stem cell pluripotency induced pluripotent stem cells umbilical cord blood spinal cord stroke Parkinson' disease Monti,Manuela Perotti,Cesare Del Fante,Claudia Cervio,Marila Redi,Carlo Alberto Stem cells: sources and therapies
description	The historical, lexical and conceptual issues embedded in stem cell biology are reviewed from technical, ethical, philosophical, judicial, clinical, economic and biopolitical perspectives. The mechanisms assigning the simultaneous capacity to self-renew and to differentiate to stem cells (immortal template DNA and asymmetric division) are evaluated in the light of the niche hypothesis for the stemness state. The induction of cell pluripotency and the different stem cells sources are presented (embryonic, adult and cord blood). We highlight the embryonic and adult stem cell properties and possible therapies while we emphasize the particular scientific and social values of cord blood donation to set up cord blood banks. The current scientific and legal frameworks of cord blood banks are reviewed at an international level as well as allogenic, dedicated and autologous donations. The expectations and the challenges in relation to present-day targeted diseases like diabetes mellitus type I, Parkinson's disease and myocardial infarction are evaluated in the light of the cellular therapies for regenerative medicine.
author	Monti,Manuela Perotti,Cesare Del Fante,Claudia Cervio,Marila Redi,Carlo Alberto
author_facet	Monti,Manuela Perotti,Cesare Del Fante,Claudia Cervio,Marila Redi,Carlo Alberto
author_sort	Monti,Manuela
title	Stem cells: sources and therapies
title_short	Stem cells: sources and therapies
title_full	Stem cells: sources and therapies
title_fullStr	Stem cells: sources and therapies
title_full_unstemmed	Stem cells: sources and therapies
title_sort	stem cells: sources and therapies
publisher	Sociedad de Biología de Chile
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300002
work_keys_str_mv	AT montimanuela stemcellssourcesandtherapies AT perotticesare stemcellssourcesandtherapies AT delfanteclaudia stemcellssourcesandtherapies AT cerviomarila stemcellssourcesandtherapies AT redicarloalberto stemcellssourcesandtherapies
_version_	1718441488865558528

Stem cells: sources and therapies

Ejemplares similares