A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus

A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus

Most cells of the developing mammalian brain derive from the ventricular (VZ) and the subventricular (SVZ) zones. The VZ is formed by the multipotent radial glia/neural stem cells (NSCs) while the SVZ harbors the rapidly proliferative neural precursor cells (NPCs). Evidence from human and animal mod...

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Main Authors: Rodríguez,Esteban M, Guerra,María M, Vío,Karin, González,César, Ortloff,Alexander, Bátiz,Luis F, Rodríguez,Sara, Jara,María C, Muñoz,Rosa I, Ortega,Eduardo, Jaque,Jaime, Guerra,Francisco, Sival,Deborah A, Dunnen,Wilfred F. A. den, Jiménez,Antonio J, Domínguez-Pinos,María D, Pérez-Fígares,José M, McAllister,James P, Johanson,Conrad
Language:English
Published: Sociedad de Biología de Chile 2012
Subjects:
hydrocephalus
abnormal neurogenesis
neural stem cells
stem cell transplantation
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300005
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