Bioethical aspects of basic research and medical applications of human stem cells

The new discoveries, the extraordinary dynamism in human stem cell (SC) research, and the great expectations of the benefits in clinical treatment of many diseases are on the edge of unparalleled advances in both: 1) the understanding of basic mechanisms of cell differentiation and development and 2...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Santos,Manuel J, Ventura-Juncá,Patricio
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2012
Materias:	Human Stem cells Basic research Bioethics Clinical trials translational research
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300013
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0716-97602012000300013
record_format	dspace
spelling	oai:scielo:S0716-976020120003000132012-12-14Bioethical aspects of basic research and medical applications of human stem cellsSantos,Manuel JVentura-Juncá,Patricio Human Stem cells Basic research Bioethics Clinical trials translational research The new discoveries, the extraordinary dynamism in human stem cell (SC) research, and the great expectations of the benefits in clinical treatment of many diseases are on the edge of unparalleled advances in both: 1) the understanding of basic mechanisms of cell differentiation and development and 2) the translation from basic research to new clinical therapies. Human stem cells are obtained from different sources, such as embryo, fetal, and adult tissues, in vitro induction (iPS cells) or transdifferentiation. The evidence that these cells are pluripotent (or multipotent), meaning they have the ability to differentiate into all body tissues or tissues of the same lineage, raises the possibility that they could regenerate diseased or damaged tissue in diseases that until now have had no effective treatments. Human stem cell research and therapy raise important bioethical considerations because of the human nature of these cells and their peculiar characteristics. Here we discuss the bioethical aspects of basic human SC research and the conditions necessary for the translation of basic preclinical research into clinical use of SC.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.45 n.3 20122012-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300013en10.4067/S0716-97602012000300013
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Human Stem cells Basic research Bioethics Clinical trials translational research
spellingShingle	Human Stem cells Basic research Bioethics Clinical trials translational research Santos,Manuel J Ventura-Juncá,Patricio Bioethical aspects of basic research and medical applications of human stem cells
description	The new discoveries, the extraordinary dynamism in human stem cell (SC) research, and the great expectations of the benefits in clinical treatment of many diseases are on the edge of unparalleled advances in both: 1) the understanding of basic mechanisms of cell differentiation and development and 2) the translation from basic research to new clinical therapies. Human stem cells are obtained from different sources, such as embryo, fetal, and adult tissues, in vitro induction (iPS cells) or transdifferentiation. The evidence that these cells are pluripotent (or multipotent), meaning they have the ability to differentiate into all body tissues or tissues of the same lineage, raises the possibility that they could regenerate diseased or damaged tissue in diseases that until now have had no effective treatments. Human stem cell research and therapy raise important bioethical considerations because of the human nature of these cells and their peculiar characteristics. Here we discuss the bioethical aspects of basic human SC research and the conditions necessary for the translation of basic preclinical research into clinical use of SC.
author	Santos,Manuel J Ventura-Juncá,Patricio
author_facet	Santos,Manuel J Ventura-Juncá,Patricio
author_sort	Santos,Manuel J
title	Bioethical aspects of basic research and medical applications of human stem cells
title_short	Bioethical aspects of basic research and medical applications of human stem cells
title_full	Bioethical aspects of basic research and medical applications of human stem cells
title_fullStr	Bioethical aspects of basic research and medical applications of human stem cells
title_full_unstemmed	Bioethical aspects of basic research and medical applications of human stem cells
title_sort	bioethical aspects of basic research and medical applications of human stem cells
publisher	Sociedad de Biología de Chile
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300013
work_keys_str_mv	AT santosmanuelj bioethicalaspectsofbasicresearchandmedicalapplicationsofhumanstemcells AT venturajuncapatricio bioethicalaspectsofbasicresearchandmedicalapplicationsofhumanstemcells
_version_	1718441491374800896

Bioethical aspects of basic research and medical applications of human stem cells

Ejemplares similares