Antioxidant, Antibacterial activity and Brine shrimp toxicity test of some Mountainous Lichens from Nepal

A total of twenty four lichen species belonging to six families were collected from mountainous region of Nepal. The methanol extracts of each species were tested for antimicrobial and antioxidant activitiesin vitro. It was found that extracts of twenty one lichen species were active againstB. subti...

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Autores principales: Paudel,Babita, Datta Bhattarai,Hari, Prasad Pandey,Durga, Seoun Hur,Jae, Gyu Hong,Soon, Kim,Il-Chan, Han Yim,Joung
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2012
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400010
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spelling oai:scielo:S0716-976020120004000102013-03-15Antioxidant, Antibacterial activity and Brine shrimp toxicity test of some Mountainous Lichens from NepalPaudel,BabitaDatta Bhattarai,HariPrasad Pandey,DurgaSeoun Hur,JaeGyu Hong,SoonKim,Il-ChanHan Yim,Joung Antibacterial Antioxidant Nepal lichens Free radicals A total of twenty four lichen species belonging to six families were collected from mountainous region of Nepal. The methanol extracts of each species were tested for antimicrobial and antioxidant activitiesin vitro. It was found that extracts of twenty one lichen species were active againstB. subtilis and seven species were active againstS. aureus. Similarly, in DPPH assay, three speciesPeltigera sp.,Cladonia sp., andCanoparmelia sp. showed comparable activity with commercial standard, BHA. In ABTS+ assay, extracts ofParmoterma sp.,Ramalina sp.,Peltigera sp. andCladonia sp. showed stronger activity than ascorbic acid. The observed data after comparison with previously published reports indicated that the high altitude lichens contain stronger antioxidant and antibacterial constituents. Similarly, the methanol extracts ofHeterodermia sp. andRamalina sp. showed comparable toxicity effect with commercial standard berberine chloride indicating a potent source of anticancer drugs.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.45 n.4 20122012-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400010en10.4067/S0716-97602012000400010
institution Scielo Chile
collection Scielo Chile
language English
topic Antibacterial
Antioxidant
Nepal lichens
Free radicals
spellingShingle Antibacterial
Antioxidant
Nepal lichens
Free radicals
Paudel,Babita
Datta Bhattarai,Hari
Prasad Pandey,Durga
Seoun Hur,Jae
Gyu Hong,Soon
Kim,Il-Chan
Han Yim,Joung
Antioxidant, Antibacterial activity and Brine shrimp toxicity test of some Mountainous Lichens from Nepal
description A total of twenty four lichen species belonging to six families were collected from mountainous region of Nepal. The methanol extracts of each species were tested for antimicrobial and antioxidant activitiesin vitro. It was found that extracts of twenty one lichen species were active againstB. subtilis and seven species were active againstS. aureus. Similarly, in DPPH assay, three speciesPeltigera sp.,Cladonia sp., andCanoparmelia sp. showed comparable activity with commercial standard, BHA. In ABTS+ assay, extracts ofParmoterma sp.,Ramalina sp.,Peltigera sp. andCladonia sp. showed stronger activity than ascorbic acid. The observed data after comparison with previously published reports indicated that the high altitude lichens contain stronger antioxidant and antibacterial constituents. Similarly, the methanol extracts ofHeterodermia sp. andRamalina sp. showed comparable toxicity effect with commercial standard berberine chloride indicating a potent source of anticancer drugs.
author Paudel,Babita
Datta Bhattarai,Hari
Prasad Pandey,Durga
Seoun Hur,Jae
Gyu Hong,Soon
Kim,Il-Chan
Han Yim,Joung
author_facet Paudel,Babita
Datta Bhattarai,Hari
Prasad Pandey,Durga
Seoun Hur,Jae
Gyu Hong,Soon
Kim,Il-Chan
Han Yim,Joung
author_sort Paudel,Babita
title Antioxidant, Antibacterial activity and Brine shrimp toxicity test of some Mountainous Lichens from Nepal
title_short Antioxidant, Antibacterial activity and Brine shrimp toxicity test of some Mountainous Lichens from Nepal
title_full Antioxidant, Antibacterial activity and Brine shrimp toxicity test of some Mountainous Lichens from Nepal
title_fullStr Antioxidant, Antibacterial activity and Brine shrimp toxicity test of some Mountainous Lichens from Nepal
title_full_unstemmed Antioxidant, Antibacterial activity and Brine shrimp toxicity test of some Mountainous Lichens from Nepal
title_sort antioxidant, antibacterial activity and brine shrimp toxicity test of some mountainous lichens from nepal
publisher Sociedad de Biología de Chile
publishDate 2012
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400010
work_keys_str_mv AT paudelbabita antioxidantantibacterialactivityandbrineshrimptoxicitytestofsomemountainouslichensfromnepal
AT dattabhattaraihari antioxidantantibacterialactivityandbrineshrimptoxicitytestofsomemountainouslichensfromnepal
AT prasadpandeydurga antioxidantantibacterialactivityandbrineshrimptoxicitytestofsomemountainouslichensfromnepal
AT seounhurjae antioxidantantibacterialactivityandbrineshrimptoxicitytestofsomemountainouslichensfromnepal
AT gyuhongsoon antioxidantantibacterialactivityandbrineshrimptoxicitytestofsomemountainouslichensfromnepal
AT kimilchan antioxidantantibacterialactivityandbrineshrimptoxicitytestofsomemountainouslichensfromnepal
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