Gastrodia elata Blume and its pure compounds protect BV-2 microglial-derived cell lines against β-amyloid: The involvement of GRP78 and CHOP

Gastrodia elata Blume and its pure compounds protect BV-2 microglial-derived cell lines against β-amyloid: The involvement of GRP78 and CHOP

Objectives: Gastrodia elata (GE) Blume (Orchidaceae) has been previously known for its therapeutic benefits against neurodegenerative diseases. Microglial activation and death have been implicated in the pathogenesis of a variety of neurodegenerative diseases, including Alzheimer's disease. In...

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Auteurs principaux: Geum-Hwa,Lee, Hyung-Ryong,Kim, Sang-Yong,Han, Bidur,Bhandary, Do-Sung,Kim, Min-Gul,Kim, Byung-Ok,So, Sun-Young,Kim, Kyu-Sik,Jo, Bo-Hee,Lee, Hee-Nam,Seo, Soo-Wan,Chae, Han-Jung,Chae
Langue:English
Publié: Sociedad de Biología de Chile 2012
Sujets:
Gastrodia elata
4HBA
GRP78
CHOP
β-amyloid
Accès en ligne:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400013
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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400013

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