Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes

Carotenoids are efficient antioxidants that are of great importance for human health. Lutein and zeaxanthin are carotinoids present in high concentrations in the human retina which are involved in the photoprotection of the human eye. Lutein may also protect the skin from ultraviolet (UV)-induced da...

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Autores principales:	Pongcharoen,Sutatip, Warnnissorn,Prateep, Lertkajornsin,Ongart, Limpeanchob,Nanteetip, Sutheerawattananonda,Manote
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2013
Materias:	Silk lutein keratinocytes UV apoptosis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000100006
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spelling	oai:scielo:S0716-976020130001000062014-09-08Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytesPongcharoen,SutatipWarnnissorn,PrateepLertkajornsin,OngartLimpeanchob,NanteetipSutheerawattananonda,Manote Silk lutein keratinocytes UV apoptosis Carotenoids are efficient antioxidants that are of great importance for human health. Lutein and zeaxanthin are carotinoids present in high concentrations in the human retina which are involved in the photoprotection of the human eye. Lutein may also protect the skin from ultraviolet (UV)-induced damage. The present study investigated the protective effect of lutein extracted from yellow silk cocoons of Bombyx mori on human keratinocytes against UVB irradiation. A human keratinocyte cell line and primary human keratinocytes were used to investigate the UVB protection effects of silk lutein and plant lutein. Silk lutein showed no cytotoxicity to keratinocytes. Treatment with silk lutein prior to UVB irradiation enhanced cell viability and cell proliferation, and reduced cell apoptosis. The protective effects of silk lutein may be superior to those of plant lutein. Silk lutein may have a benefit for protection of keratinocytes against UVB-irradiation.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.46 n.1 20132013-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000100006en10.4067/S0716-97602013000100006
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Silk lutein keratinocytes UV apoptosis
spellingShingle	Silk lutein keratinocytes UV apoptosis Pongcharoen,Sutatip Warnnissorn,Prateep Lertkajornsin,Ongart Limpeanchob,Nanteetip Sutheerawattananonda,Manote Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes
description	Carotenoids are efficient antioxidants that are of great importance for human health. Lutein and zeaxanthin are carotinoids present in high concentrations in the human retina which are involved in the photoprotection of the human eye. Lutein may also protect the skin from ultraviolet (UV)-induced damage. The present study investigated the protective effect of lutein extracted from yellow silk cocoons of Bombyx mori on human keratinocytes against UVB irradiation. A human keratinocyte cell line and primary human keratinocytes were used to investigate the UVB protection effects of silk lutein and plant lutein. Silk lutein showed no cytotoxicity to keratinocytes. Treatment with silk lutein prior to UVB irradiation enhanced cell viability and cell proliferation, and reduced cell apoptosis. The protective effects of silk lutein may be superior to those of plant lutein. Silk lutein may have a benefit for protection of keratinocytes against UVB-irradiation.
author	Pongcharoen,Sutatip Warnnissorn,Prateep Lertkajornsin,Ongart Limpeanchob,Nanteetip Sutheerawattananonda,Manote
author_facet	Pongcharoen,Sutatip Warnnissorn,Prateep Lertkajornsin,Ongart Limpeanchob,Nanteetip Sutheerawattananonda,Manote
author_sort	Pongcharoen,Sutatip
title	Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes
title_short	Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes
title_full	Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes
title_fullStr	Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes
title_full_unstemmed	Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes
title_sort	protective effect of silk lutein on ultraviolet b-irradiated human keratinocytes
publisher	Sociedad de Biología de Chile
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000100006
work_keys_str_mv	AT pongcharoensutatip protectiveeffectofsilkluteinonultravioletbirradiatedhumankeratinocytes AT warnnissornprateep protectiveeffectofsilkluteinonultravioletbirradiatedhumankeratinocytes AT lertkajornsinongart protectiveeffectofsilkluteinonultravioletbirradiatedhumankeratinocytes AT limpeanchobnanteetip protectiveeffectofsilkluteinonultravioletbirradiatedhumankeratinocytes AT sutheerawattananondamanote protectiveeffectofsilkluteinonultravioletbirradiatedhumankeratinocytes
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Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes

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