Phytochemical Profile and Qualification of Biological Activity of an Isolated Fraction of Bellis perennis

This study describes the isolation and identification of apigenin-7-O-ghicopyranoside, a flavonoid isolated from the flowers of Bellis perennis L., Asteraceae, an species with a broad spectrum of biological activities. The in vitro antioxidant activity and the inhibition of the enzyme acetylcholines...

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Autores principales:	Costa Marques,Thiago H, Santos De Melo,Cassio H, Fonseca De Carvalho,Rusbene B, Costa,Luciana M, De Souza,Alexandre A, David,Jorge M, De Lima David,Juceni P, De Freitas,Rivelilson M
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2013
Materias:	Acetylcholinesterase Antioxidant Bellis perennis Flavonoid
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000300002
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spelling	oai:scielo:S0716-976020130003000022014-01-20Phytochemical Profile and Qualification of Biological Activity of an Isolated Fraction of Bellis perennisCosta Marques,Thiago HSantos De Melo,Cassio HFonseca De Carvalho,Rusbene BCosta,Luciana MDe Souza,Alexandre ADavid,Jorge MDe Lima David,Juceni PDe Freitas,Rivelilson M Acetylcholinesterase Antioxidant Bellis perennis Flavonoid This study describes the isolation and identification of apigenin-7-O-ghicopyranoside, a flavonoid isolated from the flowers of Bellis perennis L., Asteraceae, an species with a broad spectrum of biological activities. The in vitro antioxidant activity and the inhibition of the enzyme acetylcholinesterase were evaluated. The flavonoid showed strong in vitro antioxidant potential, because of the capacity of removal of hydroxyl radicals and nitric oxide, and also prevented the formation of thiobarbituric acid-reactive substances. These parameters were inhibited at the highest concentration of ApG at rates of 77.7%, 72% and 73.4%, respectively, in addition to inhibiting acetylcholinesterase, suggesting potential use in the treatment of neurodegenerative diseases.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.46 n.3 20132013-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000300002en10.4067/S0716-97602013000300002
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Acetylcholinesterase Antioxidant Bellis perennis Flavonoid
spellingShingle	Acetylcholinesterase Antioxidant Bellis perennis Flavonoid Costa Marques,Thiago H Santos De Melo,Cassio H Fonseca De Carvalho,Rusbene B Costa,Luciana M De Souza,Alexandre A David,Jorge M De Lima David,Juceni P De Freitas,Rivelilson M Phytochemical Profile and Qualification of Biological Activity of an Isolated Fraction of Bellis perennis
description	This study describes the isolation and identification of apigenin-7-O-ghicopyranoside, a flavonoid isolated from the flowers of Bellis perennis L., Asteraceae, an species with a broad spectrum of biological activities. The in vitro antioxidant activity and the inhibition of the enzyme acetylcholinesterase were evaluated. The flavonoid showed strong in vitro antioxidant potential, because of the capacity of removal of hydroxyl radicals and nitric oxide, and also prevented the formation of thiobarbituric acid-reactive substances. These parameters were inhibited at the highest concentration of ApG at rates of 77.7%, 72% and 73.4%, respectively, in addition to inhibiting acetylcholinesterase, suggesting potential use in the treatment of neurodegenerative diseases.
author	Costa Marques,Thiago H Santos De Melo,Cassio H Fonseca De Carvalho,Rusbene B Costa,Luciana M De Souza,Alexandre A David,Jorge M De Lima David,Juceni P De Freitas,Rivelilson M
author_facet	Costa Marques,Thiago H Santos De Melo,Cassio H Fonseca De Carvalho,Rusbene B Costa,Luciana M De Souza,Alexandre A David,Jorge M De Lima David,Juceni P De Freitas,Rivelilson M
author_sort	Costa Marques,Thiago H
title	Phytochemical Profile and Qualification of Biological Activity of an Isolated Fraction of Bellis perennis
title_short	Phytochemical Profile and Qualification of Biological Activity of an Isolated Fraction of Bellis perennis
title_full	Phytochemical Profile and Qualification of Biological Activity of an Isolated Fraction of Bellis perennis
title_fullStr	Phytochemical Profile and Qualification of Biological Activity of an Isolated Fraction of Bellis perennis
title_full_unstemmed	Phytochemical Profile and Qualification of Biological Activity of an Isolated Fraction of Bellis perennis
title_sort	phytochemical profile and qualification of biological activity of an isolated fraction of bellis perennis
publisher	Sociedad de Biología de Chile
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000300002
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Phytochemical Profile and Qualification of Biological Activity of an Isolated Fraction of Bellis perennis

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