Galectin-8 binds to LFA-1, blocks its interaction with ICAM-1 and is counteracted by anti-Gal-8 autoantibodies isolated from lupus patients

Galectin-8 belongs to a family of mammalian lectins that recognize glycoconjugates present on different cell surface components and modulate a variety of cellular processes. A role of Gal-8 in the immune system has been proposed based on its effects in immune cells, including T and B lymphocytes, as...

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Autores principales: Vicuña,Lucas, Pardo,Evelyn, Curkovic,Cristóbal, Doger,Remziye, Oyanadel,Claudia, Metz,Claudia, Massardo,Loreto, González,Alfonso, Soza,Andrea
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2013
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SLE
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000300008
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