First report of in vitro selection of RNA aptamers targeted to recombinant Loxosceles laeta spider toxins

BACKGROUND: Loxoscelism is the envenomation caused by the bite of Loxosceles spp. spiders. It entails severe necrotizing skin lesions, sometimes accompanied by systemic reactions and even death. There are no diagnostic means and treatment is mostly palliative. The main toxin, found in several isofor...

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Autores principales: Sapag,Amalia, Salinas-Luypaert,Catalina, Constenla-Muñoz,Carlos
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2014
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100002
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