Multiple antibiotic susceptibility of polyphosphate kinase mutants (ppk1 and ppk2) from Pseudomonas aeruginosa PAO1 as revealed by global phenotypic analysis

Multiple antibiotic susceptibility of polyphosphate kinase mutants (ppk1 and ppk2) from Pseudomonas aeruginosa PAO1 as revealed by global phenotypic analysis

BACKGROUND: Pseudomonas aeruginosa is known to be a multidrug resistant opportunistic pathogen. Particularly, P. aeruginosa PAO1 polyphosphate kinase mutant (ppk1) is deficient in motility, quorum sensing, biofilm formation and virulence FINDINGS: By using Phenotypic Microarrays (PM) we analyzed nea...

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Autores principales: Ortiz-Severín,Javiera, Varas,Macarena, Bravo-Toncio,Catalina, Guiliani,Nicolás, Chávez,Francisco P
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2015
Materias:
Antibiotic susceptibility
Polyphosphate kinase
Pseudomonas
Phenome
Phenotypic microarrays
Multidrug resistance
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100022
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