Sox2 function as a negative regulator to control HAMP expression

Sox2 function as a negative regulator to control HAMP expression

BACKGROUND: Hepcidin, encoding by HAMP gene, is the pivotal regulator of iron metabolism, controlling the systemic absorption and transportation of irons from intracellular stores. Abnormal levels of HAMP expression alter plasma iron parameters and lead to iron metabolism disorders. Therefore,itis a...

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Autores principales: Song,Bin, Bian,Qi, Shao,Cheng-Hao, Liu,An-An, Jing,Wei, Liu,Rui, Zhang,Yi-Jie, Zhou,Ying-Qi, Li,Gang, Jin,Gang
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2015
Materias:
Sox2
Gene expression
Hepatocyte
HAMP
Iron metabolism
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100023
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