CD4+ T cells in aged or thymectomized recipients of allogeneic stem cell transplantations

CD4+ T cells in aged or thymectomized recipients of allogeneic stem cell transplantations

BACKGROUND: CD4+CD25highFOXP3+ regulatory T (Treg) cells, which include thymus-derived and peripherally induced cells, play a central role in immune regulation, and are therefore crucial to prevent graft-versus-host disease (GVHD). The increasing use of allogeneic hematopoietic stem cell transplanta...

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Autores principales: Takahashi,Hiroshi, Ikeda,Kazuhiko, Ogawa,Kazuei, Saito,Syunnichi, Ngoma,Alain M, Mashimo,Yumiko, Ueda,Koki, Furukawa,Miki, Shichishima-Nakamura,Akiko, Ohkawara,Hiroshi, Nollet,Kenneth E, Ohto,Hitoshi, Takeishi,Yasuchika
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2015
Materias:
Regulatory T cells
Allogeneic hematopoietic stem cell transplantation
Thymus
Graft-versus-host disease
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100041
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