Suppression of miR-181 a attenuates H2O2-induced death of mesenchymal stem cells by maintaining hexokinase II expression
BACKGROUND: Low survival rate of transplanted cells compromises the efficacy of cell therapy. Hexokinase II (HKII) is known to have anti-apoptotic activity through its interaction with mitochondria. The objective was to identify miRNAs targeting HKII and investigate whether miRNA-mediated modulation...
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Autores principales: | Lee,Seahyoung, Yun,Ina, Ham,Onju, Lee,Se-Yeon, Lee,Chang Yeon, Park,Jun-Hee, Lee,Jiyun, Seo,Hyang-Hee, Choi,Eunhyun, Hwang,Ki-Chul |
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Lenguaje: | English |
Publicado: |
Sociedad de Biología de Chile
2015
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Materias: | |
Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100045 |
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