Using mesenchymal stem cells as a therapy for bone regeneration and repairing

Bone is a unique tissue which could regenerate completely after injury rather than heal itself with a scar. Compared with other tissues the difference is that, during bone repairing and regeneration, after the inflammatory phase the mesenchymal stem cells (MSCs) are recruited to the injury site and...

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Autores principales:	Shao,Jin, Zhang,Weiwei, Yang,Tieyi
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2015
Materias:	Mesenchymal stem cells Bone regeneration Bone repairing Tissue engineering
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100062
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spelling	oai:scielo:S0716-976020150001000622016-02-16Using mesenchymal stem cells as a therapy for bone regeneration and repairingShao,JinZhang,WeiweiYang,Tieyi Mesenchymal stem cells Bone regeneration Bone repairing Tissue engineering Bone is a unique tissue which could regenerate completely after injury rather than heal itself with a scar. Compared with other tissues the difference is that, during bone repairing and regeneration, after the inflammatory phase the mesenchymal stem cells (MSCs) are recruited to the injury site and differentiate into either chondroblasts or osteoblasts precursors, leading to bone repairing and regeneration. Besides these two precursors, the MSCs can also differentiate into adipocyte precursors, skeletal muscle precursors and some other mesodermal cells. With this multiline-age potentiality, the MSCs are probably used to cure bone injury and other woundings in the near future. Here we will introduce the recent developments in understanding the mechanism of MSCs action in bone regeneration and repairing.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.48 20152015-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100062en10.1186/S40659-015-0053-4
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Mesenchymal stem cells Bone regeneration Bone repairing Tissue engineering
spellingShingle	Mesenchymal stem cells Bone regeneration Bone repairing Tissue engineering Shao,Jin Zhang,Weiwei Yang,Tieyi Using mesenchymal stem cells as a therapy for bone regeneration and repairing
description	Bone is a unique tissue which could regenerate completely after injury rather than heal itself with a scar. Compared with other tissues the difference is that, during bone repairing and regeneration, after the inflammatory phase the mesenchymal stem cells (MSCs) are recruited to the injury site and differentiate into either chondroblasts or osteoblasts precursors, leading to bone repairing and regeneration. Besides these two precursors, the MSCs can also differentiate into adipocyte precursors, skeletal muscle precursors and some other mesodermal cells. With this multiline-age potentiality, the MSCs are probably used to cure bone injury and other woundings in the near future. Here we will introduce the recent developments in understanding the mechanism of MSCs action in bone regeneration and repairing.
author	Shao,Jin Zhang,Weiwei Yang,Tieyi
author_facet	Shao,Jin Zhang,Weiwei Yang,Tieyi
author_sort	Shao,Jin
title	Using mesenchymal stem cells as a therapy for bone regeneration and repairing
title_short	Using mesenchymal stem cells as a therapy for bone regeneration and repairing
title_full	Using mesenchymal stem cells as a therapy for bone regeneration and repairing
title_fullStr	Using mesenchymal stem cells as a therapy for bone regeneration and repairing
title_full_unstemmed	Using mesenchymal stem cells as a therapy for bone regeneration and repairing
title_sort	using mesenchymal stem cells as a therapy for bone regeneration and repairing
publisher	Sociedad de Biología de Chile
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100062
work_keys_str_mv	AT shaojin usingmesenchymalstemcellsasatherapyforboneregenerationandrepairing AT zhangweiwei usingmesenchymalstemcellsasatherapyforboneregenerationandrepairing AT yangtieyi usingmesenchymalstemcellsasatherapyforboneregenerationandrepairing
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Using mesenchymal stem cells as a therapy for bone regeneration and repairing

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