BJ-1108, a 6-Amino-2,4,5-trimethylpyridin-3-ol analogue, regulates differentiation of Th1 and Th17 cells to ameliorate experimental autoimmune encephalomyelitis

BJ-1108, a 6-Amino-2,4,5-trimethylpyridin-3-ol analogue, regulates differentiation of Th1 and Th17 cells to ameliorate experimental autoimmune encephalomyelitis

Abstract Background CD4+ T cells play an important role in the initiation of an immune response by providing help to other cells. Among the helper T subsets, interferon-γ (IFN-γ)-secreting T helper 1 (Th1) and IL-17-secreting T helper 17 (Th17) cells are indispensable for clearan...

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Autores principales: Kang,Youra, Timilshina,Maheshwor, Nam,Tae-gyu, Jeong,Byeong-Seon, Chang,Jae-Hoon
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2017
Materias:
BJ-1108
Th1/Th17 cell
Differentiation
EAE
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100202
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