Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro

Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro

Abstract Background Ubiquitin specific peptidase 39 (USP39), an essential factor in the assembly of the mature spliceosome complex, has an aberrant expression in several cancer. However, its function and the corresponding mechanism on human osteosarcoma has not been fully explored yet. Methods T...

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Autores principales: Gan,Zhihua, Han,Kun, Lin,Shuchen, Hu,Haiyan, Shen,Zan, Min,Daliu
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2017
Materias:
Cell cycle
Migration
Osteosarcoma
Proliferation
USP39
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100210
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