S100A8 inhibits PDGF-induced proliferation of airway smooth muscle cells dependent on the receptor for advanced glycation end-products

S100A8 inhibits PDGF-induced proliferation of airway smooth muscle cells dependent on the receptor for advanced glycation end-products

Abstract Background Airway remodeling is a key feature of asthma, characterized by increased proliferation of airway smooth muscle cells (ASMCs). S100A8 is a calcium‑binding protein with a potential to regulate cell proliferation. Here, the effect of exogenous S100A8 protein on the proli...

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Autores principales: Xu,Yu‑Dong, Wang,Yu, Yin,Lei‑Miao, Peng,Ling‑Ling, Park,Gyoung‑Hee, Yang,Yong‑Qing
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2017
Materias:
S100A8
Airway smooth muscle cells
Cell proliferation
The receptor for advanced glycation end‑ products
Platelet‑derived growth factor
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100216
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