Differential roles for pathogenicity islands SPI-13 and SPI-8 in the interaction of Salmonella Enteritidis and Salmonella Typhi with murine and human macrophages

Differential roles for pathogenicity islands SPI-13 and SPI-8 in the interaction of Salmonella Enteritidis and Salmonella Typhi with murine and human macrophages

Abstract Background Salmonella pathogenicity island (SPI)-13 is conserved in many serovars of S. enterica, including S. Enteritidis, S. Typhimurium and S. Gallinarum. However, it is absent in typhoid serovars such as S. Typhi and Paratyphi A, which carry SPI-8 at the same genomic location. Because...

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Autores principales: Espinoza,Rodrigo A., Silva‑Valenzuela,Cecilia A., Amaya,Fernando A., Urrutia,Ítalo M., Contreras,Inés, Santiviago,Carlos A.
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2017
Materias:
Salmonella
Enteritidis
Typhi
SPI-13
SPI-8
Macrophages
RAW264.7
THP-1
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100402
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