Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines
Abstract Background: Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), an enzyme required for de novo purine biosynthesis, is associated with and involved in tumorigenesis. This study aimed to evaluate the role of PAICS in human breast can...
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Autores principales: | Meng,Minjun, Chen,Yanling, Jia,Jianbo, Li,Lianghui, Yang,Sumei |
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Lenguaje: | English |
Publicado: |
Sociedad de Biología de Chile
2018
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Materias: | |
Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602018000100220 |
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