Minimal residual disease in prostate cancer patients after primary treatment: theoretical considerations, evidence and possible use in clinical management

Abstract Minimal residual disease is that not detected by conventional imaging studies and clinically the patient remains disease free. However, with time these dormant cells will awaken and disease progression occurs, resulting in clinically and radiological detectable metastatic disease. This revi...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Murray,Nigel P.
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2018
Materias:	Prostate cancer Circulating tumor cells Tumor cell dissemination Dormancy Micrometastasis Phenotype Treatment
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602018000100503
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0716-97602018000100503
record_format	dspace
spelling	oai:scielo:S0716-976020180001005032018-10-18Minimal residual disease in prostate cancer patients after primary treatment: theoretical considerations, evidence and possible use in clinical managementMurray,Nigel P. Prostate cancer Circulating tumor cells Tumor cell dissemination Dormancy Micrometastasis Phenotype Treatment Abstract Minimal residual disease is that not detected by conventional imaging studies and clinically the patient remains disease free. However, with time these dormant cells will awaken and disease progression occurs, resulting in clinically and radiological detectable metastatic disease. This review addresses the concept of tumor cell dissemination from the primary tumor, the micrometastatic niche and tumor cell survival and finally the clinical utility of detecting and characterizing these tumor cells in order to guide management decisions in treating patients with prostate cancer.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.51 20182018-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602018000100503en10.1186/s40659-018-0180-9
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Prostate cancer Circulating tumor cells Tumor cell dissemination Dormancy Micrometastasis Phenotype Treatment
spellingShingle	Prostate cancer Circulating tumor cells Tumor cell dissemination Dormancy Micrometastasis Phenotype Treatment Murray,Nigel P. Minimal residual disease in prostate cancer patients after primary treatment: theoretical considerations, evidence and possible use in clinical management
description	Abstract Minimal residual disease is that not detected by conventional imaging studies and clinically the patient remains disease free. However, with time these dormant cells will awaken and disease progression occurs, resulting in clinically and radiological detectable metastatic disease. This review addresses the concept of tumor cell dissemination from the primary tumor, the micrometastatic niche and tumor cell survival and finally the clinical utility of detecting and characterizing these tumor cells in order to guide management decisions in treating patients with prostate cancer.
author	Murray,Nigel P.
author_facet	Murray,Nigel P.
author_sort	Murray,Nigel P.
title	Minimal residual disease in prostate cancer patients after primary treatment: theoretical considerations, evidence and possible use in clinical management
title_short	Minimal residual disease in prostate cancer patients after primary treatment: theoretical considerations, evidence and possible use in clinical management
title_full	Minimal residual disease in prostate cancer patients after primary treatment: theoretical considerations, evidence and possible use in clinical management
title_fullStr	Minimal residual disease in prostate cancer patients after primary treatment: theoretical considerations, evidence and possible use in clinical management
title_full_unstemmed	Minimal residual disease in prostate cancer patients after primary treatment: theoretical considerations, evidence and possible use in clinical management
title_sort	minimal residual disease in prostate cancer patients after primary treatment: theoretical considerations, evidence and possible use in clinical management
publisher	Sociedad de Biología de Chile
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602018000100503
work_keys_str_mv	AT murraynigelp minimalresidualdiseaseinprostatecancerpatientsafterprimarytreatmenttheoreticalconsiderationsevidenceandpossibleuseinclinicalmanagement
_version_	1718441581628882944

Minimal residual disease in prostate cancer patients after primary treatment: theoretical considerations, evidence and possible use in clinical management

Ejemplares similares