Vitexin induces apoptosis through mitochondrial pathway and PI3K/Akt/mTOR signaling in human non-small cell lung cancer A549 cells

Vitexin induces apoptosis through mitochondrial pathway and PI3K/Akt/mTOR signaling in human non-small cell lung cancer A549 cells

Abstract Background: Currently, the prognosis of patients with non-small cell lung cancer (NSCLC) remains dismal; hence, it is critical to identify effective anti-NSCLC agents with limited side effects. This study aimed to evaluate the therapeutic potential of flavonoid compound vitexin in human NS...

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Autores principales: Liu,Xiaoli, Jiang,Qingfeng, Liu,Huaimin, Luo,Suxia
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2019
Materias:
Non-small cell lung cancer
Vitexin
Mitochondrial dysfunction
PI3K/Akt/mTOR signaling
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602019000100206
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