Notum attenuates HBV-related liver fibrosis through inhibiting Wnt 5a mediated non-canonical pathways

Notum attenuates HBV-related liver fibrosis through inhibiting Wnt 5a mediated non-canonical pathways

Abstract Background: Non-canonical Wnt pathways play important roles in liver fibrosis. Notum is a newly discovered inhibitor to Wnt proteins. This study was to investigate anti-fibrotic effects of Notum. Methods: 53 patients with hepatitis B virus (HBV) infection as well as a cell co-culture syst...

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Autores principales: Li,Wenting, Yu,Xiaolan, Zhu,Chuanlong, Wang,Zheng, Zhao,Zonghao, Li,Yi, Zhang,Yonghong
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2019
Materias:
Notum
Wnt signaling pathway
HBV
Liver fibrosis
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602019000100208
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