CoCl2 simulated hypoxia induce cell proliferation and alter the expression pattern of hypoxia associated genes involved in angiogenesis and apoptosis

Abstract Background/aims: Hypoxia microenvironment plays a crucial role during tumor progression and it tends to exhibit poor prognosis and make resistant to various conventional therapies. HIF-1α acts as an important transcriptional regulator directly or indirectly associated with genes i...

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Autores principales: Rana,Nishant Kumar, Singh,Priya, Koch,Biplob
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2019
Materias:
p53
BAX
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602019000100210
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