CoCl2 simulated hypoxia induce cell proliferation and alter the expression pattern of hypoxia associated genes involved in angiogenesis and apoptosis
Abstract Background/aims: Hypoxia microenvironment plays a crucial role during tumor progression and it tends to exhibit poor prognosis and make resistant to various conventional therapies. HIF-1α acts as an important transcriptional regulator directly or indirectly associated with genes i...
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Lenguaje: | English |
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Sociedad de Biología de Chile
2019
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Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602019000100210 |
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