Chronic prostatitis alters the prostatic microenvironment and accelerates preneoplastic lesions in C57BL/6 mice

Chronic prostatitis alters the prostatic microenvironment and accelerates preneoplastic lesions in C57BL/6 mice

Abstract Background: Chronic prostatitis has been supposed to be associated with preneoplastic lesions and cancer development. The objective of this study was to examine how chronic inflammation results in a prostatic microenvironment and gene mutation in C57BL/6 mice. Methods: Immune and bacteria...

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Main Authors: Gao,Yong, Wei,Lijuan, Wang,Chenbang, Huang,Yuanjie, Li,Weidong, Li,Tianyu, Mo,Chaohua, Qin,Huali, Zhong,Xiaoge, Wang,Yun, Tan,Aihua, Mo,Zengnan, Jiang,Yonghua, Hu,Yanling
Language:English
Published: Sociedad de Biología de Chile 2019
Subjects:
Chronic prostatitis
Prostatitis mouse model
Proliferative inflammatory atrophy
Prostatic intraepithelial neoplasia
Somatic genome mutation
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602019000100228
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