Linc-OIP5 in the breast cancer cells regulates angiogenesis of human umbilical vein endothelial cells through YAP1/Notch/NRP1 signaling circuit at a tumor microenvironment

Linc-OIP5 in the breast cancer cells regulates angiogenesis of human umbilical vein endothelial cells through YAP1/Notch/NRP1 signaling circuit at a tumor microenvironment

Abstract Background: LincRNAs have been revealed to be tightly associated with various tumorigeneses and cancer development, but the roles of specific lincRNA on tumor-related angiogenesis was hardly studied. Here, we aimed to investigate whether linc-OIP5 in breast cancer cells affects the angioge...

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Autores principales: Zhu,Qing, Li,Jingchao, Wu,Qi, Cheng,Yongxia, Zheng,Huizhe, Zhan,Tao, Wang,Hongwei, Yang,Yue, Wang,Hongyan, Liu,Ye, Guo,Sufen
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2020
Materias:
Tumor microenvironment
Angiogenesis
Linc-OIP5
Signal transduction
Breast cancer
HUVECs
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602020000100204
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