Caspase-7 deficiency in Chinese hamster ovary cells reduces cell proliferation and viability

Caspase-7 deficiency in Chinese hamster ovary cells reduces cell proliferation and viability

Abstract Background: Chinese hamster ovary (CHO) cells are the most commonly used mammalian host cell In the commercial-scale production of biopharmaceutical proteins. Modification of genes involved in apoptosis may improve the productivity of CHO cells. Executive caspases, including caspases 3 and...

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Autores principales: Safari,Fatemeh, Farajnia,Safar, Behbahani,Abbas Behzad, Zarredar,Habib, Barekati-Mowahed,Mazyar, Dehghani,Hesam
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2020
Materias:
CHO cells
Apoptosis
CRISPR-associated protein 9
Caspase 7
Cell proliferatio
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602020000100239
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