Tauroursodeoxycholic acid attenuates neuronal apoptosis via the TGR5/ SIRT3 pathway after subarachnoid hemorrhage in rats

Tauroursodeoxycholic acid attenuates neuronal apoptosis via the TGR5/ SIRT3 pathway after subarachnoid hemorrhage in rats

Abstract Background: Neuronal apoptosis plays a critical event in the pathogenesis of early brain injury after subarachnoid hemorrhage (SAH). This study investigated the roles of Tauroursodeoxycholic acid (TUDCA) in attenuate neuronal apoptosis and underlying mechanisms after SAH. Methods: Sprague...

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Autores principales: Wu,Huihui, Yu,Nini, Wang,Xia, Yang,Yina, Liang,Hui
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2020
Materias:
TUDCA
Apoptosis
Neuroprotection
Subarachnoid hemorrhage
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602020000100243
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