DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice

DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice

Abstract Background: Peroxisome proliferator-activated receptor alpha (PPARα) is associated with diabetic retinopathy (DR), and the underlying mechanism is still unclear. Aim of this work was to investigate the mechanism of PPARα in DR. Methods: Human retinal capillary pericytes...

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Autores principales: Zhu,Ying, Wang,Xinru, Zhou,Xiaoyun, Ding,Lexi, Liu,Dan, Xu,Huizhuo
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2021
Materias:
DNMT1
PPARα
DNA methylation
Apoptosis
Diabetic retinopathy
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602021000100221
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