ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE

The present work aims at establishing the toxic effects on spermatogenesis of a single injection of the organophosphorous agropesticide Parathion, administered to immature male mice. Seven days old animals were injected intraperitoneally with 1/3 the LD50. Body and testicular weights were measured....

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Autores principales:	Sobarzo,Cristián, Bustos-Obregón,Eduardo
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2000
Materias:	Agropesticides Spermatogenic Mice
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-98682000000100008
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spelling	oai:scielo:S0716-986820000001000082005-10-04ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICESobarzo,CristiánBustos-Obregón,Eduardo Agropesticides Spermatogenic Mice The present work aims at establishing the toxic effects on spermatogenesis of a single injection of the organophosphorous agropesticide Parathion, administered to immature male mice. Seven days old animals were injected intraperitoneally with 1/3 the LD50. Body and testicular weights were measured. Quantitative as well as qualitative analysis of seminiferous tubules and germ cell populations were done for control and injected mice 8, 16, 28 and 50 days after injection. The cytotoxic effect of the pesticide is substantiated by a decrease of body and testis weight and an early damage of germ cells in treated mice. The effect is reversible and recovers at longer intervalsinfo:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaRevista chilena de anatomía v.18 n.1 20002000-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-98682000000100008en10.4067/S0716-98682000000100008
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Agropesticides Spermatogenic Mice
spellingShingle	Agropesticides Spermatogenic Mice Sobarzo,Cristián Bustos-Obregón,Eduardo ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
description	The present work aims at establishing the toxic effects on spermatogenesis of a single injection of the organophosphorous agropesticide Parathion, administered to immature male mice. Seven days old animals were injected intraperitoneally with 1/3 the LD50. Body and testicular weights were measured. Quantitative as well as qualitative analysis of seminiferous tubules and germ cell populations were done for control and injected mice 8, 16, 28 and 50 days after injection. The cytotoxic effect of the pesticide is substantiated by a decrease of body and testis weight and an early damage of germ cells in treated mice. The effect is reversible and recovers at longer intervals
author	Sobarzo,Cristián Bustos-Obregón,Eduardo
author_facet	Sobarzo,Cristián Bustos-Obregón,Eduardo
author_sort	Sobarzo,Cristián
title	ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
title_short	ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
title_full	ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
title_fullStr	ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
title_full_unstemmed	ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE
title_sort	acute effect of parathion on the seminiferous epithelium of immature mice
publisher	Sociedad Chilena de Anatomía
publishDate	2000
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-98682000000100008
work_keys_str_mv	AT sobarzocristian acuteeffectofparathionontheseminiferousepitheliumofimmaturemice AT bustosobregoneduardo acuteeffectofparathionontheseminiferousepitheliumofimmaturemice
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ACUTE EFFECT OF PARATHION ON THE SEMINIFEROUS EPITHELIUM OF IMMATURE MICE

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