Formation of highly porous biodegradable scaffolds for tissue engineering
In recent years, lack of donor organs has caused many to consider tissue engineering methods as means to replace diseased or damaged organs. This newly-emerging field uses tissue-specific cells in a three-dimensional organization, provided by a scaffolding material, to return functionality of the or...
Guardado en:
| Autores principales: | , |
|---|---|
| Lenguaje: | English |
| Publicado: |
Pontificia Universidad Católica de Valparaíso
2000
|
| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582000000200003 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:scielo:S0717-34582000000200003 |
|---|---|
| record_format |
dspace |
| spelling |
oai:scielo:S0717-345820000002000032003-10-13Formation of highly porous biodegradable scaffolds for tissue engineeringMikos,Antonios G.Temenoff,Johnna S. In recent years, lack of donor organs has caused many to consider tissue engineering methods as means to replace diseased or damaged organs. This newly-emerging field uses tissue-specific cells in a three-dimensional organization, provided by a scaffolding material, to return functionality of the organ. For these applications, the choice of scaffolding material is crucial to the success of the technique. In addition to the chemical properties of the material, physical properties such as surface area for cell attachment are essential. Various methods of creating pores in these materials to increase surface area are reviewed here. Scaffolds formed using the different techniques, which include fiber bonding, solvent casting/particulate leaching, gas foaming and phase separation, are compared on the basis of porosity, pore size, and promotion of tissue growth. <A NAME="Article"></A>info:eu-repo/semantics/openAccessPontificia Universidad Católica de ValparaísoElectronic Journal of Biotechnology v.3 n.2 20002000-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582000000200003en |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| description |
In recent years, lack of donor organs has caused many to consider tissue engineering methods as means to replace diseased or damaged organs. This newly-emerging field uses tissue-specific cells in a three-dimensional organization, provided by a scaffolding material, to return functionality of the organ. For these applications, the choice of scaffolding material is crucial to the success of the technique. In addition to the chemical properties of the material, physical properties such as surface area for cell attachment are essential. Various methods of creating pores in these materials to increase surface area are reviewed here. Scaffolds formed using the different techniques, which include fiber bonding, solvent casting/particulate leaching, gas foaming and phase separation, are compared on the basis of porosity, pore size, and promotion of tissue growth. <A NAME="Article"></A> |
| author |
Mikos,Antonios G. Temenoff,Johnna S. |
| spellingShingle |
Mikos,Antonios G. Temenoff,Johnna S. Formation of highly porous biodegradable scaffolds for tissue engineering |
| author_facet |
Mikos,Antonios G. Temenoff,Johnna S. |
| author_sort |
Mikos,Antonios G. |
| title |
Formation of highly porous biodegradable scaffolds for tissue engineering |
| title_short |
Formation of highly porous biodegradable scaffolds for tissue engineering |
| title_full |
Formation of highly porous biodegradable scaffolds for tissue engineering |
| title_fullStr |
Formation of highly porous biodegradable scaffolds for tissue engineering |
| title_full_unstemmed |
Formation of highly porous biodegradable scaffolds for tissue engineering |
| title_sort |
formation of highly porous biodegradable scaffolds for tissue engineering |
| publisher |
Pontificia Universidad Católica de Valparaíso |
| publishDate |
2000 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582000000200003 |
| work_keys_str_mv |
AT mikosantoniosg formationofhighlyporousbiodegradablescaffoldsfortissueengineering AT temenoffjohnnas formationofhighlyporousbiodegradablescaffoldsfortissueengineering |
| _version_ |
1718441689075417088 |