Normalization of elevated liver enzymes due to V-1 Immunitor therapy
V-1 Immunitor (V1) is an oral AIDS vaccine currently being used as a therapeutic modality by HIV-positive patients. Upon interim analysis of phase I safety trial it has been discovered that patients who had elevated liver enzymes aspartate (AST/SGOT) and alanine (ALT/SGPT) aminotransferases have exp...
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| Lenguaje: | English |
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Pontificia Universidad Católica de Valparaíso
2003
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oai:scielo:S0717-345820030001000102003-08-18Normalization of elevated liver enzymes due to V-1 Immunitor therapyJirathitikal,VichaiMetadilogkul,OrapunBourinbaiar,Aldar S. V-1 Immunitor (V1) is an oral AIDS vaccine currently being used as a therapeutic modality by HIV-positive patients. Upon interim analysis of phase I safety trial it has been discovered that patients who had elevated liver enzymes aspartate (AST/SGOT) and alanine (ALT/SGPT) aminotransferases have experienced the reduction of enzyme levels back to normal. Two other hepatitis markers alkaline phosphatase and bilirubin have also decreased. V1s effect may be hepatitis-specific since liver enzymes in normal patients treated with V1 have not changed and three patients who were Hepatitis B antigen positive at baseline became negative after therapy. The results suggest that V1 supplementation reduces hepatic damage caused by hepatitis viral infection.info:eu-repo/semantics/openAccessPontificia Universidad Católica de ValparaísoElectronic Journal of Biotechnology v.6 n.1 20032003-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582003000100010en |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| description |
V-1 Immunitor (V1) is an oral AIDS vaccine currently being used as a therapeutic modality by HIV-positive patients. Upon interim analysis of phase I safety trial it has been discovered that patients who had elevated liver enzymes aspartate (AST/SGOT) and alanine (ALT/SGPT) aminotransferases have experienced the reduction of enzyme levels back to normal. Two other hepatitis markers alkaline phosphatase and bilirubin have also decreased. V1s effect may be hepatitis-specific since liver enzymes in normal patients treated with V1 have not changed and three patients who were Hepatitis B antigen positive at baseline became negative after therapy. The results suggest that V1 supplementation reduces hepatic damage caused by hepatitis viral infection. |
| author |
Jirathitikal,Vichai Metadilogkul,Orapun Bourinbaiar,Aldar S. |
| spellingShingle |
Jirathitikal,Vichai Metadilogkul,Orapun Bourinbaiar,Aldar S. Normalization of elevated liver enzymes due to V-1 Immunitor therapy |
| author_facet |
Jirathitikal,Vichai Metadilogkul,Orapun Bourinbaiar,Aldar S. |
| author_sort |
Jirathitikal,Vichai |
| title |
Normalization of elevated liver enzymes due to V-1 Immunitor therapy |
| title_short |
Normalization of elevated liver enzymes due to V-1 Immunitor therapy |
| title_full |
Normalization of elevated liver enzymes due to V-1 Immunitor therapy |
| title_fullStr |
Normalization of elevated liver enzymes due to V-1 Immunitor therapy |
| title_full_unstemmed |
Normalization of elevated liver enzymes due to V-1 Immunitor therapy |
| title_sort |
normalization of elevated liver enzymes due to v-1 immunitor therapy |
| publisher |
Pontificia Universidad Católica de Valparaíso |
| publishDate |
2003 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582003000100010 |
| work_keys_str_mv |
AT jirathitikalvichai normalizationofelevatedliverenzymesduetov1immunitortherapy AT metadilogkulorapun normalizationofelevatedliverenzymesduetov1immunitortherapy AT bourinbaiaraldars normalizationofelevatedliverenzymesduetov1immunitortherapy |
| _version_ |
1718441711344025600 |