Infection of Caenorhabditis elegans by Salmonella typhi Ty2

Several serovars of Salmonella infect and kill the nematode C. elegans. However, here we report that Salmonella typhi Ty2, a representative strain of this human pathogen, readily infects the intestinal lining of C. elegans without significantly affecting its viability. Our observation suggests exten...

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Autores principales: Santander,Javier, Espinoza,Juan Carlos, Campano,María Soledad, Robeson,James
Lenguaje:English
Publicado: Pontificia Universidad Católica de Valparaíso 2003
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582003000200008
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Sumario:Several serovars of Salmonella infect and kill the nematode C. elegans. However, here we report that Salmonella typhi Ty2, a representative strain of this human pathogen, readily infects the intestinal lining of C. elegans without significantly affecting its viability. Our observation suggests extending the use of the C. elegans model system for the study of host parasite relationships, to address problems concerning the biology of S. typhi.