Influence of medium constituents on the biosynthesis of cephalosporin-C

Acremonium chrysogenum NCIM 1069 was used for the biosynthesis of cephalosporin-C (CPC) in batch mode of cultivation. The effect of different medium constituents for better yield of CPC was thoroughly investigated. From the results of the fermentation, it was found that ammonium sulphate as inorgani...

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Autores principales:	Kumar Nigam,Vinod, Verma,Ruchi, Kumar,Abhishek, Kundu,Subir, Ghosh,Purnendu
Lenguaje:	English
Publicado:	Pontificia Universidad Católica de Valparaíso 2007
Materias:	Acremonium chrysogenum batch fermentation cephalosporin-C methionine stirred tank bioreactor
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582007000200007
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spelling	oai:scielo:S0717-345820070002000072007-10-29Influence of medium constituents on the biosynthesis of cephalosporin-CKumar Nigam,VinodVerma,RuchiKumar,AbhishekKundu,SubirGhosh,Purnendu Acremonium chrysogenum batch fermentation cephalosporin-C methionine stirred tank bioreactor Acremonium chrysogenum NCIM 1069 was used for the biosynthesis of cephalosporin-C (CPC) in batch mode of cultivation. The effect of different medium constituents for better yield of CPC was thoroughly investigated. From the results of the fermentation, it was found that ammonium sulphate as inorganic nitrogen source and methionine at the concentration of 0.4% are most suitable for higher yield of antibiotic. The variation in the C/N ratio on the biosynthesis of CPC showed that a C/N ratio of 8.0 is most suitable for maximum production of CPCinfo:eu-repo/semantics/openAccessPontificia Universidad Católica de ValparaísoElectronic Journal of Biotechnology v.10 n.2 20072007-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582007000200007en10.4067/S0717-34582007000200007
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Acremonium chrysogenum batch fermentation cephalosporin-C methionine stirred tank bioreactor
spellingShingle	Acremonium chrysogenum batch fermentation cephalosporin-C methionine stirred tank bioreactor Kumar Nigam,Vinod Verma,Ruchi Kumar,Abhishek Kundu,Subir Ghosh,Purnendu Influence of medium constituents on the biosynthesis of cephalosporin-C
description	Acremonium chrysogenum NCIM 1069 was used for the biosynthesis of cephalosporin-C (CPC) in batch mode of cultivation. The effect of different medium constituents for better yield of CPC was thoroughly investigated. From the results of the fermentation, it was found that ammonium sulphate as inorganic nitrogen source and methionine at the concentration of 0.4% are most suitable for higher yield of antibiotic. The variation in the C/N ratio on the biosynthesis of CPC showed that a C/N ratio of 8.0 is most suitable for maximum production of CPC
author	Kumar Nigam,Vinod Verma,Ruchi Kumar,Abhishek Kundu,Subir Ghosh,Purnendu
author_facet	Kumar Nigam,Vinod Verma,Ruchi Kumar,Abhishek Kundu,Subir Ghosh,Purnendu
author_sort	Kumar Nigam,Vinod
title	Influence of medium constituents on the biosynthesis of cephalosporin-C
title_short	Influence of medium constituents on the biosynthesis of cephalosporin-C
title_full	Influence of medium constituents on the biosynthesis of cephalosporin-C
title_fullStr	Influence of medium constituents on the biosynthesis of cephalosporin-C
title_full_unstemmed	Influence of medium constituents on the biosynthesis of cephalosporin-C
title_sort	influence of medium constituents on the biosynthesis of cephalosporin-c
publisher	Pontificia Universidad Católica de Valparaíso
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582007000200007
work_keys_str_mv	AT kumarnigamvinod influenceofmediumconstituentsonthebiosynthesisofcephalosporinc AT vermaruchi influenceofmediumconstituentsonthebiosynthesisofcephalosporinc AT kumarabhishek influenceofmediumconstituentsonthebiosynthesisofcephalosporinc AT kundusubir influenceofmediumconstituentsonthebiosynthesisofcephalosporinc AT ghoshpurnendu influenceofmediumconstituentsonthebiosynthesisofcephalosporinc
_version_	1718441766542114816

Influence of medium constituents on the biosynthesis of cephalosporin-C

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