Biocatalytic oxidative kinetic resolution of (±)-4-(chlorophenyl)phenylmethanol by Nocardia corallina B-276

Biocatalytic oxidative kinetic resolution of (±)-4-(chlorophenyl)phenylmethanol by Nocardia corallina B-276

Chiral diarylmethanols are versatile building blocks for the preparation of biologically active substances, but they are difficult to obtain in enantiopure form. We used Nocardia corallina B-276 for the oxidative kinetic resolution of (±)-4-(chlorophenyl)phenylmethanol, 1. Two experimental methods w...

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Autores principales: Ramírez,Mario A., Pérez,Herminia I., Manjarrez,Norberto, Solís,Aida, Luna,Héctor, Cassani,Julia
Lenguaje:English
Publicado: Pontificia Universidad Católica de Valparaíso 2008
Materias:
4-chlorobenzophenone
biocatalysis
microbial oxidation
resolution
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582008000400002
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