Characterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymer
Gelatin, chitosan and hyaluronic acid are natural components used to prepare polymeric scaffold in tissue engineering. The physical properties of these materials confer an appropriate microenvironment for cells, which can be used as a regeneration system for skin and cartilage. In this work, we prep...
Guardado en:
| Autores principales: | , , , , , , , , , , , , |
|---|---|
| Lenguaje: | English |
| Publicado: |
Pontificia Universidad Católica de Valparaíso
2010
|
| Materias: | |
| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582010000500020 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:scielo:S0717-34582010000500020 |
|---|---|
| record_format |
dspace |
| spelling |
oai:scielo:S0717-345820100005000202011-05-24Characterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymerEnrione,JavierOsorio,FernandoLópez,DanielWeinstein-Oppenheimer,CarolineFuentes,Miguel ACeriani,RicardoBrown,Donald IAlbornoz,FernandoSánchez,ElizabethVillalobos,PatricioSomoza,Rodrigo AYoung,Manuel EAcevedo,Cristian A chitosan fibrin gelatin hyaluronic acid scaffold Gelatin, chitosan and hyaluronic acid are natural components used to prepare polymeric scaffold in tissue engineering. The physical properties of these materials confer an appropriate microenvironment for cells, which can be used as a regeneration system for skin and cartilage. In this work, we prepared and characterized a Gelatin/Chitosan/Hyaluronan lyophilized-polymer. Physical properties of lyophilized-polymer changed slightly with moisture, but when polymer was totally hydrated the elasticity changed significantly. Thermophysical characterisation indicated that temperatures higher than 30ºC could modify irreversibly the polymeric matrix probably due to protein denaturation. Besides, we used the polymer as scaffold to prepare a biosynthetic-skin, reporting biological behaviour and its mechanical properties.info:eu-repo/semantics/openAccessPontificia Universidad Católica de ValparaísoElectronic Journal of Biotechnology v.13 n.5 20102010-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582010000500020en |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
chitosan fibrin gelatin hyaluronic acid scaffold |
| spellingShingle |
chitosan fibrin gelatin hyaluronic acid scaffold Enrione,Javier Osorio,Fernando López,Daniel Weinstein-Oppenheimer,Caroline Fuentes,Miguel A Ceriani,Ricardo Brown,Donald I Albornoz,Fernando Sánchez,Elizabeth Villalobos,Patricio Somoza,Rodrigo A Young,Manuel E Acevedo,Cristian A Characterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymer |
| description |
Gelatin, chitosan and hyaluronic acid are natural components used to prepare polymeric scaffold in tissue engineering. The physical properties of these materials confer an appropriate microenvironment for cells, which can be used as a regeneration system for skin and cartilage. In this work, we prepared and characterized a Gelatin/Chitosan/Hyaluronan lyophilized-polymer. Physical properties of lyophilized-polymer changed slightly with moisture, but when polymer was totally hydrated the elasticity changed significantly. Thermophysical characterisation indicated that temperatures higher than 30ºC could modify irreversibly the polymeric matrix probably due to protein denaturation. Besides, we used the polymer as scaffold to prepare a biosynthetic-skin, reporting biological behaviour and its mechanical properties. |
| author |
Enrione,Javier Osorio,Fernando López,Daniel Weinstein-Oppenheimer,Caroline Fuentes,Miguel A Ceriani,Ricardo Brown,Donald I Albornoz,Fernando Sánchez,Elizabeth Villalobos,Patricio Somoza,Rodrigo A Young,Manuel E Acevedo,Cristian A |
| author_facet |
Enrione,Javier Osorio,Fernando López,Daniel Weinstein-Oppenheimer,Caroline Fuentes,Miguel A Ceriani,Ricardo Brown,Donald I Albornoz,Fernando Sánchez,Elizabeth Villalobos,Patricio Somoza,Rodrigo A Young,Manuel E Acevedo,Cristian A |
| author_sort |
Enrione,Javier |
| title |
Characterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymer |
| title_short |
Characterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymer |
| title_full |
Characterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymer |
| title_fullStr |
Characterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymer |
| title_full_unstemmed |
Characterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymer |
| title_sort |
characterization of a gelatin/chitosan/hyaluronan scaffold-polymer |
| publisher |
Pontificia Universidad Católica de Valparaíso |
| publishDate |
2010 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582010000500020 |
| work_keys_str_mv |
AT enrionejavier characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT osoriofernando characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT lopezdaniel characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT weinsteinoppenheimercaroline characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT fuentesmiguela characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT cerianiricardo characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT browndonaldi characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT albornozfernando characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT sanchezelizabeth characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT villalobospatricio characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT somozarodrigoa characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT youngmanuele characterizationofagelatinchitosanhyaluronanscaffoldpolymer AT acevedocristiana characterizationofagelatinchitosanhyaluronanscaffoldpolymer |
| _version_ |
1718441824845037568 |