Complement dependent cytotoxicity activity of therapeutic antibody fragments is acquired by immunogenic glycan coupling
Oligosaccharides are implicated in the development of the immune response notably in complement activation. Anti-tumoural immunotherapy by monoclonal antibodies (mAbs) offers some advantages to chemotherapy including cell targeting but some of them are inefficient to generate cytotoxicity dependent...
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| Auteurs principaux: | , , , , , |
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| Langue: | English |
| Publié: |
Pontificia Universidad Católica de Valparaíso
2012
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| Accès en ligne: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582012000500005 |
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