Production of antibody fragment (Fab) throughout Escherichia coli fed-batch fermentation process: Changes in titre, location and form of product
Background: Recombinant proteins, including antibodies and antibody fragments, often contain disulfide bond bridges that are necessary for their folding, stability and function. Production of disulfide-bond-containing proteins in the periplasm of Escherichia coli has been very useful, due to unique...
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| Language: | English |
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Pontificia Universidad Católica de Valparaíso
2013
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| Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582013000300009 |
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