A C1069G SNP of the MC4R gene and its association with economic traits in Korean native cattle (brown, brindle, and black)

Background: The melanocortin-4 receptor gene (MC4R) plays an important role in regulating food intake and body weight in mammals. In the present study, we identified the MC4R gene in native Korean brown, brindle, and black cattle by polymerase chain reaction restriction fragment length polymorphism...

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Autores principales:	Lee,Youngsub, Park,Sairom, Kim,Hun, Lee,Seung Kyu, Kim,Jin Woo, Lee,Hak Kyo, Jeong,Dong Kee, Lee,Sung Jin
Lenguaje:	English
Publicado:	Pontificia Universidad Católica de Valparaíso 2013
Materias:	economic trait marbling scores MC4R gene PCR-RFLP SNP
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582013000500014
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spelling	oai:scielo:S0717-345820130005000142014-09-17A C1069G SNP of the MC4R gene and its association with economic traits in Korean native cattle (brown, brindle, and black)Lee,YoungsubPark,SairomKim,HunLee,Seung KyuKim,Jin WooLee,Hak KyoJeong,Dong KeeLee,Sung Jin economic trait marbling scores MC4R gene PCR-RFLP SNP Background: The melanocortin-4 receptor gene (MC4R) plays an important role in regulating food intake and body weight in mammals. In the present study, we identified the MC4R gene in native Korean brown, brindle, and black cattle by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP), and investigated its association with economic traits. A total of 413 cattle from the three breeds were tested for backfat thickness, carcass weight, longissimus muscle area, and marbling score, and statistical data were analyzed using the SAS program. Results: The C allele had the highest frequency in brown and brindle cattle, and the G allele frequency was highest in black cattle. The C1069G SNP was significantly (p < 0.05) associated with only marbling scores in brown and brindle cattle but no significant association was detected between the marbling scores and polymorphism in black cattle. Conclusions: These results suggest that a C1069G SNP of the MC4R gene may be useful as a genetic marker for marbling scores in Korean brown and brindle cattle.info:eu-repo/semantics/openAccessPontificia Universidad Católica de ValparaísoElectronic Journal of Biotechnology v.16 n.5 20132013-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582013000500014en10.2225/vol16-issue5-fulltext-5
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	economic trait marbling scores MC4R gene PCR-RFLP SNP
spellingShingle	economic trait marbling scores MC4R gene PCR-RFLP SNP Lee,Youngsub Park,Sairom Kim,Hun Lee,Seung Kyu Kim,Jin Woo Lee,Hak Kyo Jeong,Dong Kee Lee,Sung Jin A C1069G SNP of the MC4R gene and its association with economic traits in Korean native cattle (brown, brindle, and black)
description	Background: The melanocortin-4 receptor gene (MC4R) plays an important role in regulating food intake and body weight in mammals. In the present study, we identified the MC4R gene in native Korean brown, brindle, and black cattle by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP), and investigated its association with economic traits. A total of 413 cattle from the three breeds were tested for backfat thickness, carcass weight, longissimus muscle area, and marbling score, and statistical data were analyzed using the SAS program. Results: The C allele had the highest frequency in brown and brindle cattle, and the G allele frequency was highest in black cattle. The C1069G SNP was significantly (p < 0.05) associated with only marbling scores in brown and brindle cattle but no significant association was detected between the marbling scores and polymorphism in black cattle. Conclusions: These results suggest that a C1069G SNP of the MC4R gene may be useful as a genetic marker for marbling scores in Korean brown and brindle cattle.
author	Lee,Youngsub Park,Sairom Kim,Hun Lee,Seung Kyu Kim,Jin Woo Lee,Hak Kyo Jeong,Dong Kee Lee,Sung Jin
author_facet	Lee,Youngsub Park,Sairom Kim,Hun Lee,Seung Kyu Kim,Jin Woo Lee,Hak Kyo Jeong,Dong Kee Lee,Sung Jin
author_sort	Lee,Youngsub
title	A C1069G SNP of the MC4R gene and its association with economic traits in Korean native cattle (brown, brindle, and black)
title_short	A C1069G SNP of the MC4R gene and its association with economic traits in Korean native cattle (brown, brindle, and black)
title_full	A C1069G SNP of the MC4R gene and its association with economic traits in Korean native cattle (brown, brindle, and black)
title_fullStr	A C1069G SNP of the MC4R gene and its association with economic traits in Korean native cattle (brown, brindle, and black)
title_full_unstemmed	A C1069G SNP of the MC4R gene and its association with economic traits in Korean native cattle (brown, brindle, and black)
title_sort	c1069g snp of the mc4r gene and its association with economic traits in korean native cattle (brown, brindle, and black)
publisher	Pontificia Universidad Católica de Valparaíso
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582013000500014
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A C1069G SNP of the MC4R gene and its association with economic traits in Korean native cattle (brown, brindle, and black)

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