One-pot synthesis of graphene-chitosan nanocomposite modified carbon paste electrode for selective determination of dopamine

Background A simple, rapid, low-cost and environmentally friendly method was developed to determine dopamine (DA) in the presence of ascorbic (AA) and uric acid (UA) based on a novel technique to prepare a graphene-chitosan (GR-CS) nanocomposite and modify it on the surface of carbon paste electrode...

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Autores principales:	Liu,Chang, Zhang,Jing, Yifeng,E, Yue,Jingli, Chen,Lianshan, Li,Donghui
Lenguaje:	English
Publicado:	Pontificia Universidad Católica de Valparaíso 2014
Materias:	Dopamine Selective determination Surface modification of carbon paste electrode Technique of one-pot synthesis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582014000400007
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spelling	oai:scielo:S0717-345820140004000072014-09-02One-pot synthesis of graphene-chitosan nanocomposite modified carbon paste electrode for selective determination of dopamineLiu,ChangZhang,JingYifeng,EYue,JingliChen,LianshanLi,Donghui Dopamine Selective determination Surface modification of carbon paste electrode Technique of one-pot synthesis Background A simple, rapid, low-cost and environmentally friendly method was developed to determine dopamine (DA) in the presence of ascorbic (AA) and uric acid (UA) based on a novel technique to prepare a graphene-chitosan (GR-CS) nanocomposite and modify it on the surface of carbon paste electrode (CPE). For our design, CS acts as a media to disperse and stabilize GR, and then GR plays a key role to selective and sensitive determination of DA. Results Under physiological conditions, the linear range for dopamine was determined from 1 × 10- 4 to 2 × 10- 7 mol/L with a good correlation coefficient of 0.9961 in the presence of 1000-fold interference of AA and UA. The detection limit was estimated to be 9.82 × 10- 8 mol/L (S/N = 3). In order to study the stability and reproducibility, GR/CS/CPE underwent successive measurements in 10 times and then tested once a d for 30 d. The result exhibited 98.25% and 91.62% activities compared with the original peak current after 10-time measurements and 30-d storage. Conclusion The GR/CS/CPE has wide linear concentration range, low detection limit, and good reproducibility and stability, which suggests that our investigations provide a promising alternative for clinic DA determination.info:eu-repo/semantics/openAccessPontificia Universidad Católica de ValparaísoElectronic Journal of Biotechnology v.17 n.4 20142014-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582014000400007en10.1016/j.ejbt.2014.04.013
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Dopamine Selective determination Surface modification of carbon paste electrode Technique of one-pot synthesis
spellingShingle	Dopamine Selective determination Surface modification of carbon paste electrode Technique of one-pot synthesis Liu,Chang Zhang,Jing Yifeng,E Yue,Jingli Chen,Lianshan Li,Donghui One-pot synthesis of graphene-chitosan nanocomposite modified carbon paste electrode for selective determination of dopamine
description	Background A simple, rapid, low-cost and environmentally friendly method was developed to determine dopamine (DA) in the presence of ascorbic (AA) and uric acid (UA) based on a novel technique to prepare a graphene-chitosan (GR-CS) nanocomposite and modify it on the surface of carbon paste electrode (CPE). For our design, CS acts as a media to disperse and stabilize GR, and then GR plays a key role to selective and sensitive determination of DA. Results Under physiological conditions, the linear range for dopamine was determined from 1 × 10- 4 to 2 × 10- 7 mol/L with a good correlation coefficient of 0.9961 in the presence of 1000-fold interference of AA and UA. The detection limit was estimated to be 9.82 × 10- 8 mol/L (S/N = 3). In order to study the stability and reproducibility, GR/CS/CPE underwent successive measurements in 10 times and then tested once a d for 30 d. The result exhibited 98.25% and 91.62% activities compared with the original peak current after 10-time measurements and 30-d storage. Conclusion The GR/CS/CPE has wide linear concentration range, low detection limit, and good reproducibility and stability, which suggests that our investigations provide a promising alternative for clinic DA determination.
author	Liu,Chang Zhang,Jing Yifeng,E Yue,Jingli Chen,Lianshan Li,Donghui
author_facet	Liu,Chang Zhang,Jing Yifeng,E Yue,Jingli Chen,Lianshan Li,Donghui
author_sort	Liu,Chang
title	One-pot synthesis of graphene-chitosan nanocomposite modified carbon paste electrode for selective determination of dopamine
title_short	One-pot synthesis of graphene-chitosan nanocomposite modified carbon paste electrode for selective determination of dopamine
title_full	One-pot synthesis of graphene-chitosan nanocomposite modified carbon paste electrode for selective determination of dopamine
title_fullStr	One-pot synthesis of graphene-chitosan nanocomposite modified carbon paste electrode for selective determination of dopamine
title_full_unstemmed	One-pot synthesis of graphene-chitosan nanocomposite modified carbon paste electrode for selective determination of dopamine
title_sort	one-pot synthesis of graphene-chitosan nanocomposite modified carbon paste electrode for selective determination of dopamine
publisher	Pontificia Universidad Católica de Valparaíso
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582014000400007
work_keys_str_mv	AT liuchang onepotsynthesisofgraphenechitosannanocompositemodifiedcarbonpasteelectrodeforselectivedeterminationofdopamine AT zhangjing onepotsynthesisofgraphenechitosannanocompositemodifiedcarbonpasteelectrodeforselectivedeterminationofdopamine AT yifenge onepotsynthesisofgraphenechitosannanocompositemodifiedcarbonpasteelectrodeforselectivedeterminationofdopamine AT yuejingli onepotsynthesisofgraphenechitosannanocompositemodifiedcarbonpasteelectrodeforselectivedeterminationofdopamine AT chenlianshan onepotsynthesisofgraphenechitosannanocompositemodifiedcarbonpasteelectrodeforselectivedeterminationofdopamine AT lidonghui onepotsynthesisofgraphenechitosannanocompositemodifiedcarbonpasteelectrodeforselectivedeterminationofdopamine
_version_	1718441893947244544

One-pot synthesis of graphene-chitosan nanocomposite modified carbon paste electrode for selective determination of dopamine

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