Inhibitory effect of lotus seedpod oligomeric procyanidins on advanced glycation end product formation in a lactose-lysine model system
Background Industrial food processing induces protein glycation modifications and toxic advanced glycation end products (AGEs) which affect human health. Therefore, it is of interest to monitor AGEs in food processing. The present study was carried out to investigate the influence of lotus seedpod o...
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Pontificia Universidad Católica de Valparaíso
2015
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oai:scielo:S0717-345820150002000022015-05-08Inhibitory effect of lotus seedpod oligomeric procyanidins on advanced glycation end product formation in a lactose-lysine model systemWu,QianLi,Shu-YiYang,TingXiao,JuanChu,Qian-MeiLi,TingXie,Bi-JunSun,Zhi-Da Advanced glycation end products (AGEs) Lactose Lotus seedpod oligomeric procyanidins (LSOPC) Lysine Maillard reaction Background Industrial food processing induces protein glycation modifications and toxic advanced glycation end products (AGEs) which affect human health. Therefore, it is of interest to monitor AGEs in food processing. The present study was carried out to investigate the influence of lotus seedpod oligomeric procyanidin (LSOPC) concentrations, solution pH value and metal ions on AGE formation by heat treatment of lactose-lysine model solutions. Ne-(carboxymethyl) lysine (CML), as one of the common AGEs was also determined by HPLC-MS/MS in this experiment. Results The results showed that LSOPC can inhibit the formation of AGEs effectively at higher concentrations, lower temperature, and it can reverse the promotion function of metal ions because of its high inhibition activity. Also, LSOPC can inhibit CML formation in the Maillard reaction as well. Conclusion These results indicated that LSOPC could be used as functional food ingredients to inhibit AGE formation.info:eu-repo/semantics/openAccessPontificia Universidad Católica de ValparaísoElectronic Journal of Biotechnology v.18 n.2 20152015-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582015000200002en10.1016/j.ejbt.2014.10.005 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
Advanced glycation end products (AGEs) Lactose Lotus seedpod oligomeric procyanidins (LSOPC) Lysine Maillard reaction |
| spellingShingle |
Advanced glycation end products (AGEs) Lactose Lotus seedpod oligomeric procyanidins (LSOPC) Lysine Maillard reaction Wu,Qian Li,Shu-Yi Yang,Ting Xiao,Juan Chu,Qian-Mei Li,Ting Xie,Bi-Jun Sun,Zhi-Da Inhibitory effect of lotus seedpod oligomeric procyanidins on advanced glycation end product formation in a lactose-lysine model system |
| description |
Background Industrial food processing induces protein glycation modifications and toxic advanced glycation end products (AGEs) which affect human health. Therefore, it is of interest to monitor AGEs in food processing. The present study was carried out to investigate the influence of lotus seedpod oligomeric procyanidin (LSOPC) concentrations, solution pH value and metal ions on AGE formation by heat treatment of lactose-lysine model solutions. Ne-(carboxymethyl) lysine (CML), as one of the common AGEs was also determined by HPLC-MS/MS in this experiment. Results The results showed that LSOPC can inhibit the formation of AGEs effectively at higher concentrations, lower temperature, and it can reverse the promotion function of metal ions because of its high inhibition activity. Also, LSOPC can inhibit CML formation in the Maillard reaction as well. Conclusion These results indicated that LSOPC could be used as functional food ingredients to inhibit AGE formation. |
| author |
Wu,Qian Li,Shu-Yi Yang,Ting Xiao,Juan Chu,Qian-Mei Li,Ting Xie,Bi-Jun Sun,Zhi-Da |
| author_facet |
Wu,Qian Li,Shu-Yi Yang,Ting Xiao,Juan Chu,Qian-Mei Li,Ting Xie,Bi-Jun Sun,Zhi-Da |
| author_sort |
Wu,Qian |
| title |
Inhibitory effect of lotus seedpod oligomeric procyanidins on advanced glycation end product formation in a lactose-lysine model system |
| title_short |
Inhibitory effect of lotus seedpod oligomeric procyanidins on advanced glycation end product formation in a lactose-lysine model system |
| title_full |
Inhibitory effect of lotus seedpod oligomeric procyanidins on advanced glycation end product formation in a lactose-lysine model system |
| title_fullStr |
Inhibitory effect of lotus seedpod oligomeric procyanidins on advanced glycation end product formation in a lactose-lysine model system |
| title_full_unstemmed |
Inhibitory effect of lotus seedpod oligomeric procyanidins on advanced glycation end product formation in a lactose-lysine model system |
| title_sort |
inhibitory effect of lotus seedpod oligomeric procyanidins on advanced glycation end product formation in a lactose-lysine model system |
| publisher |
Pontificia Universidad Católica de Valparaíso |
| publishDate |
2015 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582015000200002 |
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