Overproduction of clavulanic acid by extractive fermentation
Background Clavulanic acid is an important beta-lactamase inhibitor produced as a secondary metabolite by the actinomycete Streptomyces clavuligerus. Clavulanic acid is chemically unstable; therefore, it is degraded during bacterial cultivation. In this work, the adsorbents clinoptilolite, activated...
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Autores principales: | Lopes Costa,Cecília Ladeira, Colli Badino,Alberto |
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Lenguaje: | English |
Publicado: |
Pontificia Universidad Católica de Valparaíso
2015
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Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582015000300003 |
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