MALARIA IN ANCIENT EGYPT: PALEOIMMUNOLOGICAL INVESTIGATION ON PREDYNASTIC MUMMIFIED REMAINS

We examined samples from the Marro's Collection, belonging to the Anthropological and Ethnographic Museum of Turin, to determine the presence of malaria antigens. The specimens we assessed belong to predynastic mummies (3.200 B.C.) from Gebelen. For detection of malaria, we applied a paleoimmun...

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Autores principales:	Rabino Massa,Emma, Cerutti,Nicoletta, Marin D. Savoia,A.
Lenguaje:	English
Publicado:	Universidad de Tarapacá. Facultad de Ciencias Sociales y Jurídicas. Departamento de Antropología 2000
Materias:	Plasmodium falciparum paleoimmunology ancient Egypt
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-73562000000100003
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spelling	oai:scielo:S0717-735620000001000032006-01-04MALARIA IN ANCIENT EGYPT: PALEOIMMUNOLOGICAL INVESTIGATION ON PREDYNASTIC MUMMIFIED REMAINSRabino Massa,EmmaCerutti,NicolettaMarin D. Savoia,A. Plasmodium falciparum paleoimmunology ancient Egypt We examined samples from the Marro's Collection, belonging to the Anthropological and Ethnographic Museum of Turin, to determine the presence of malaria antigens. The specimens we assessed belong to predynastic mummies (3.200 B.C.) from Gebelen. For detection of malaria, we applied a paleoimmunological investigation, using an immunoenzymatic assay (Para Sight™ - F test) revealing trophozoite derived from Plasmodium falciparum histidine rich protein-2 antigen (PfHRP-2) on skin, muscle and bone samples. Excluding only the poorly conserved mummies, we analyzed about fifty of the 85 individuals of this collection. In these Egyptian mummies we have detected the presence of malaria, according to the observation of thalassemia in the same mummies, as reported in previous paper (<A HREF="#Rabino1977">E. Rabino Massa 1977</A>). In parallel, we undertook a morphological study on the skeletons to detect macroscopic signs of malaria, to confirm immunological results. The skulls exhibit the "hair-on-end" pattern, while the vertebrae often display compression of the central portions of the vertebral bodies. The results obtained suggest an incidence of malaria of about 40% in the mummies of the Gebelen group examined. These data are compatible with other observations effected on populations living in similar ecological conditions of malarial areasinfo:eu-repo/semantics/openAccessUniversidad de Tarapacá. Facultad de Ciencias Sociales y Jurídicas. Departamento de AntropologíaChungará (Arica) v.32 n.1 20002000-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-73562000000100003en10.4067/S0717-73562000000100003
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Plasmodium falciparum paleoimmunology ancient Egypt
spellingShingle	Plasmodium falciparum paleoimmunology ancient Egypt Rabino Massa,Emma Cerutti,Nicoletta Marin D. Savoia,A. MALARIA IN ANCIENT EGYPT: PALEOIMMUNOLOGICAL INVESTIGATION ON PREDYNASTIC MUMMIFIED REMAINS
description	We examined samples from the Marro's Collection, belonging to the Anthropological and Ethnographic Museum of Turin, to determine the presence of malaria antigens. The specimens we assessed belong to predynastic mummies (3.200 B.C.) from Gebelen. For detection of malaria, we applied a paleoimmunological investigation, using an immunoenzymatic assay (Para Sight™ - F test) revealing trophozoite derived from Plasmodium falciparum histidine rich protein-2 antigen (PfHRP-2) on skin, muscle and bone samples. Excluding only the poorly conserved mummies, we analyzed about fifty of the 85 individuals of this collection. In these Egyptian mummies we have detected the presence of malaria, according to the observation of thalassemia in the same mummies, as reported in previous paper (<A HREF="#Rabino1977">E. Rabino Massa 1977</A>). In parallel, we undertook a morphological study on the skeletons to detect macroscopic signs of malaria, to confirm immunological results. The skulls exhibit the "hair-on-end" pattern, while the vertebrae often display compression of the central portions of the vertebral bodies. The results obtained suggest an incidence of malaria of about 40% in the mummies of the Gebelen group examined. These data are compatible with other observations effected on populations living in similar ecological conditions of malarial areas
author	Rabino Massa,Emma Cerutti,Nicoletta Marin D. Savoia,A.
author_facet	Rabino Massa,Emma Cerutti,Nicoletta Marin D. Savoia,A.
author_sort	Rabino Massa,Emma
title	MALARIA IN ANCIENT EGYPT: PALEOIMMUNOLOGICAL INVESTIGATION ON PREDYNASTIC MUMMIFIED REMAINS
title_short	MALARIA IN ANCIENT EGYPT: PALEOIMMUNOLOGICAL INVESTIGATION ON PREDYNASTIC MUMMIFIED REMAINS
title_full	MALARIA IN ANCIENT EGYPT: PALEOIMMUNOLOGICAL INVESTIGATION ON PREDYNASTIC MUMMIFIED REMAINS
title_fullStr	MALARIA IN ANCIENT EGYPT: PALEOIMMUNOLOGICAL INVESTIGATION ON PREDYNASTIC MUMMIFIED REMAINS
title_full_unstemmed	MALARIA IN ANCIENT EGYPT: PALEOIMMUNOLOGICAL INVESTIGATION ON PREDYNASTIC MUMMIFIED REMAINS
title_sort	malaria in ancient egypt: paleoimmunological investigation on predynastic mummified remains
publisher	Universidad de Tarapacá. Facultad de Ciencias Sociales y Jurídicas. Departamento de Antropología
publishDate	2000
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-73562000000100003
work_keys_str_mv	AT rabinomassaemma malariainancientegyptpaleoimmunologicalinvestigationonpredynasticmummifiedremains AT ceruttinicoletta malariainancientegyptpaleoimmunologicalinvestigationonpredynasticmummifiedremains AT marindsavoiaa malariainancientegyptpaleoimmunologicalinvestigationonpredynasticmummifiedremains
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MALARIA IN ANCIENT EGYPT: PALEOIMMUNOLOGICAL INVESTIGATION ON PREDYNASTIC MUMMIFIED REMAINS

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